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4995278
C3
Description
Complement pathways
No tags specified
immuno
c3
complement
pod
exam 1
professional
Mind Map by
Amaal Salhieh
, updated more than 1 year ago
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Created by
Amaal Salhieh
over 8 years ago
21
0
0
Resource summary
C3
iC3
D Cleaves B into Ba and Bb
Ba is released
Bb + iC3 = iC3b
iC3b
cleaves C3 into C3a and C3b
C3b attaches to pathogen
D cleaves B into Ba and Bb
C3b + Bb = C3bBb
alternative C3 convertase
alternative C5 convertase
C3b2Bb
Cleaves C5 into C5a and C5b
C5b initiates membrane-attack complex
C6, C7, C8 bind
C9 polymerizes
C5a
Analphylatoxins
+ C3b
Ba is released
B
C3a
classical C3 convertase
C4bC2a
C2a
C2
C2b
C4b
C4
cleaves
MASP2
Lectin Pathway
C1s
CRP
binds to C1q
C1r cuts itself
C1r cuts other C1r
<-- C1r cuts both C1s
C1s
Classical Pathway
C4a
Anaphylatoxins
soluble C3 convertase
B
Hydrolysis
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