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5281920
Immunology part 2
Description
Immunology by shalihin
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afiqahilin@gmail.com
fisya1810@gmail.com
shaallya96@gmail.com
Mind Map by
shalihin
, updated more than 1 year ago
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Created by
shalihin
over 8 years ago
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Resource summary
Immunology part 2
Third line defence
Adaptive immune response
characteristics
response higher in the second infection
specific
immune activated after infection starts
memory stored
organs of lymphatic system
primary
Absence of antigen
secondary
Antigen-driven immune cell
development of T and B cells
lymphocyte
B cells
bone marrow
T cells
thymus
Have markers
bind to receptors on other cells
transmit and receive message
bind to antigens
receptors
Major histocompatibility complex (MHC)
class 1
all nucleated cell
class 2
antigen-presenting cell
macrophages
dendritic cells
B cells
class 3
protein associated with the complement system
Cluster of differentiation (CD)
CD4
MHC class 2
CD8
MHC class 1
Antigen-specific
recognise one type of unique antigen
diverse key and lock shapes
T and B cell carrying receptors
clones receptors
clonal deletion
eliminate lymphocytes that recognise self-antigens
Presentation antigen
Antigen
provoke immune response
antigenicity depends on
complexity
size
foreignness
presented by APCs
B cells
immunoglobulins
IgG, IgA, IgM, IgE, IgD
dendritic cells
macrophages
T-cell receptors (TCR)
co-receptors
CD4 and CD*
T-cell response
APCs activate T cells
stimulate into
T helper cells (Th)
activate other cells
macrophages
B cells
Tc cells
Memory T cells
store immunological memory
Regulatory T cells (Treg)
prevent excessive inflammation and autoimmunity
Cytotoxic T cells (Tc)
attact
infected host cells
cancerous host cell
foreign cells
secrete granzymes and perforins
leads to perforations and apoptosis
B-cell response
T-independent
T-dependent
T-helper cell
Differentiate
memory B cells
Regulatory B cells
Plasma cells
antibodies
Neutralisation
Oponisation
Agglutination
Antitoxin action
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