Biological approach to treating OCD

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AS - Level Psychology (Psychopathology) Mind Map on Biological approach to treating OCD, created by Jess Hughes on 04/05/2016.
Jess Hughes
Mind Map by Jess Hughes, updated more than 1 year ago
Jess Hughes
Created by Jess Hughes over 8 years ago
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Resource summary

Biological approach to treating OCD
  1. SSRI's
    1. Common for OCD as well as depression
      1. Normalising the worry circuit
        1. Helps increase serotonin levels
        2. Reduce anxiety found with OCD
          1. E.g. prozac
            1. Serotonin is released into synapse from one neuron.
              1. Targets receptor cells on the receiving neuron at receptor sites and afterwards is re-absorbed by the initial neuron sending the message.
                1. In order to increases serotonin at the synapse and increases stimulation to receiving neuron, the re-uptake is inhibited
            2. Anti anxiety's (Benzodiazepines)
              1. Xanax, valium and librium
                1. Slow activity of CNS by enhancing the activity of GABA (gamma-aminobutyric acid) a neurotransmitter which has a quietening effect on the neurons in the brain
                  1. Reacts with GABA receptors on receiving neurons which opens a channel allowing a flow of chloride ions into the neuron
                    1. Chloride makes it harder for the neuron to be stimulated by other NT's, slowing its activity and creating a relaxed feeling.
                2. Tricyclic's
                  1. Primarily used for OCD rather than depression
                    1. Block the transporter mechanism that re-absorbs serotonin and noradrenaline into the pre-synaptic cell after it has fired.
                      1. More NT's are left in synapse, prolonging their activity and easing transmission into next impulse
                        1. Target more than 1 NT
                          1. Bad side effects, i.e. hallucinations so are used only when SSRI's fail
                          2. D - Cycloserine is used to treat anxiety and possibly OCD. Is an antibiotic for TB. Enhances GABA transmission
                            1. Side effects
                              1. Sometimes outweigh the benefits of the drug
                                1. Insomnia, hallucinations, aggressiveness can be overwhelming and worse than the OCD behaviours they're aiming to combat.
                                2. Sometimes are bearable due to the drug having a positive impact on symptoms
                                  1. I.e. slight dizziness and nausea outweigh OCD behaviours like cleaning hands until bleeding
                                3. Not lasting cure
                                  1. Only help to ease symptoms rather than actually curing the behaviour in the first place
                                    1. Likely to relapse in weeks after stopping medication
                                  2. Effectiveness
                                    1. Drug trials show that drugs are effective in treating OCD
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