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7035923
A viral infection
Description
Mind Map on A viral infection, created by Salma Mk on 18/11/2016.
Mind Map by
Salma Mk
, updated more than 1 year ago
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Created by
Salma Mk
almost 8 years ago
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Resource summary
A viral infection
HIV
Structure
retrovirus
stages
primary infection
1 to 3 months
includes window period
period between infection and production of antibodies
4 to 8 weeks
highly infectious person
HIV RNA copies are very high, CD4 count is low
CD4 count 800-1500/ml
clinical latency
CD4 count increases, HIV RNA copies decrease
8 to 10 years
asymtpomatic period
AIDS
2 to 3 years
CD4 count less than 200/ml
immune system weakens
prone to opportunistic infections and malignancies
kaposi sarcoma
Tuberculosis
meningitis
candidiasis
modes of transmission
Sexually
most common
parentrally
unsafe blood
drug addicts
mother to child (vertical transmission)
in utero
during birth
breast milk
prevention
health education
safe sex
sterilised needles
ART for pregnant HIV+ women
screening of organs and blood donors
investigations
test for
viral infection
viral load
PCR test
quantitation of viral load
positive in first 10 days
p24 antigen
useful for window period
immune response
immunoglobulins
cellular response
2 steps
confirmatory tests
western blot
immunofluorescense
screening tests
ELISA
latex agglutination
management and follow up
antiretroviral therapy
protease inhibitor
inhibits action of HIV aspartyl protease
entry/fusion inhibitor
inhibits fusion and entry of virus to target host cell
reverse transcriptase inhibitor
NRTIs
NNRTIs
inhibits formation of DNA from Viral RNA
integrase inhibitor
inhibits integration of viral cDNA to host DNA
follow up
virologic failure
therapeutic drug monitoring
cd4 cell recovery and persistent inflammation
stages of grief
denial
anger
bargaining
depression
acceptance
Media attachments
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e48abd25-7953-49f7-a159-4efe648fb7e6 (image/png)
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