A viral infection

Description

Mind Map on A viral infection, created by Salma Mk on 18/11/2016.
Salma Mk
Mind Map by Salma Mk, updated more than 1 year ago
Salma Mk
Created by Salma Mk about 8 years ago
55
0

Resource summary

A viral infection
  1. HIV
    1. Structure
      1. retrovirus
      2. stages
        1. primary infection
          1. 1 to 3 months
            1. includes window period
              1. period between infection and production of antibodies
                1. 4 to 8 weeks
              2. highly infectious person
                1. HIV RNA copies are very high, CD4 count is low
                2. CD4 count 800-1500/ml
                3. clinical latency
                  1. CD4 count increases, HIV RNA copies decrease
                    1. 8 to 10 years
                      1. asymtpomatic period
                      2. AIDS
                        1. 2 to 3 years
                          1. CD4 count less than 200/ml
                          2. immune system weakens
                            1. prone to opportunistic infections and malignancies
                              1. kaposi sarcoma
                                1. Tuberculosis
                                  1. meningitis
                                    1. candidiasis
                              2. modes of transmission
                                1. Sexually
                                  1. most common
                                  2. parentrally
                                    1. unsafe blood
                                      1. drug addicts
                                      2. mother to child (vertical transmission)
                                        1. in utero
                                          1. during birth
                                            1. breast milk
                                            2. prevention
                                              1. health education
                                                1. safe sex
                                                  1. sterilised needles
                                                    1. ART for pregnant HIV+ women
                                                      1. screening of organs and blood donors
                                                    2. investigations
                                                      1. test for
                                                        1. viral infection
                                                          1. viral load
                                                            1. PCR test
                                                              1. quantitation of viral load
                                                                1. positive in first 10 days
                                                              2. p24 antigen
                                                                1. useful for window period
                                                              3. immune response
                                                                1. immunoglobulins
                                                                  1. cellular response
                                                                2. 2 steps
                                                                  1. confirmatory tests
                                                                    1. western blot
                                                                      1. immunofluorescense
                                                                      2. screening tests
                                                                        1. ELISA
                                                                          1. latex agglutination
                                                                      3. management and follow up
                                                                        1. antiretroviral therapy
                                                                          1. protease inhibitor
                                                                            1. inhibits action of HIV aspartyl protease
                                                                            2. entry/fusion inhibitor
                                                                              1. inhibits fusion and entry of virus to target host cell
                                                                              2. reverse transcriptase inhibitor
                                                                                1. NRTIs
                                                                                  1. NNRTIs
                                                                                    1. inhibits formation of DNA from Viral RNA
                                                                                    2. integrase inhibitor
                                                                                      1. inhibits integration of viral cDNA to host DNA
                                                                                    3. follow up
                                                                                      1. virologic failure
                                                                                        1. therapeutic drug monitoring
                                                                                          1. cd4 cell recovery and persistent inflammation
                                                                                        2. stages of grief
                                                                                          1. denial
                                                                                            1. anger
                                                                                              1. bargaining
                                                                                                1. depression
                                                                                                  1. acceptance
                                                                                          Show full summary Hide full summary

                                                                                          Similar

                                                                                          Shapes of molecules and intermolecular forces
                                                                                          eimearkelly3
                                                                                          Unit 1 Sociology: Family Types
                                                                                          ArcticCourtney
                                                                                          Biology Unit 1
                                                                                          hannahsanderson1
                                                                                          Chemistry 3 Extracting Metals Core GCSE
                                                                                          Chloe Roberts
                                                                                          IB SL Biology: Cells
                                                                                          mcgowan-w-10
                                                                                          GCSE English Language Overview
                                                                                          philip.ellis
                                                                                          Macbeth - Charcters
                                                                                          a.agagon
                                                                                          A-level Maths: Key Differention Formulae
                                                                                          Andrea Leyden
                                                                                          Life in Germany
                                                                                          Ben C
                                                                                          PSBD TEST # 3
                                                                                          yog thapa
                                                                                          PSBD/PSCOD/ASSD-New
                                                                                          Yuvraj Sunar