Different tissues work together and are grouped together to form organs
Organs work together as body systems
Organisms begin life as a zygote - a fertilised egg
The zygote divides by mitosis to form an embryo
In humans up to and including the 8 cell stage all the cells are identical. These cells are embryonic stem cells
After the 8 cell stage the cells become specialised and different tissues form
In adults stem cells remain in certain parts of the body. They can only differentiate into certain cell types
In specialised cells, only the genes are needed to enable that cell to function, as that type of cell is switched on
Cell specialisation in Plants
Specialised plant cells from tissues such as the xylem, which transports water and mineral salts, and phloem, which transports the products of photosynthesis
Tissues are organised into organs eg stems flowers etc...
Cells in regions called meristems are unspecialised
When meristem cells divide into 2 the new cell produced can differentiate into different cell types (the other stays a meristem cell)
Meristems produce growth and height and width
Plant Clones
New plants can be grown by placing the cut end of a shoot in water or soil
Roots grow at the base of the stem, while the shoot continues to grow
Pieces of plants that have meristems and are used to produce clones are called cuttings
Cuttings
Can be used to produce new plants with the same desirable features as the parent
Produce clones that are genetically identical to the parent plant
Root growth in cuttings is promoted by plant hormones
Another method of cloning is called tissue culture - a small piece of tissue or a few cells are placed on agar jelly containing nutrients and plant hormones, this makes it grow into a small plant
Plant hormones called auxins are included in the agar for tissue culture and in hormone rooting powder
Auxins increase cell division and cell enlargement, promoting growth of the plant tissue
Plant growth and development
Plant growth and development is affected by the environment
Plants response to the direction of light is called phototropism
Plants grow towards the light so they are positively phototropic
By growing towards light plants increase their chances of survival
The plant hormone called auxin is produced in the growing tip of plant shoots. It moves down the shoot and produces growth below the tip
If a plant is illuminated by one side
The auxin produced in the tip is distributed towards the shaded side
The auxin produces growth on the shaded side
The shoot grows towards the lights
Mitosis
Is the type of cell division that makes something grow
Mitosis results in 2 daughter cells coming from the original cell which are genetically identical
Process
1. Before mitosis the DNA in each chromosome is copied, each chromosome doubles itself
2. The chromosomes line up in the middle of the cell
3. One chromosome of each pair go into each daughter cell
BEFORE mitosis the cell increases in size, the number of organelles increase
Meiosis
Is the cell division used to produce gametes (sex cells) sperm and egg cells
In humans, gametes only contain 23 chromosomes not 46
Meiosis produces 4 daughter cells
Process
1. The chromosomes are duplicated and they pair up (like in mitosis)
2. The cell divides into 2
3. Those cells again divide into 2 to produce 4 daughter cells
Chromosomes, genes and DNA
Chromosomes
Are thread-like structures found in the nucleus
Are made from a DNA molecule
Can be grouped into pairs (pairs of 23 in humans)
DNA
A DNA molecule is a double helix
The DNA molecule is 2 strands facing eachother
The strands of DNA are made up of units linked by chemicals called bases
There are 4 bases A, T, G, C
T links with A - AT TA
G links with C - GC CG
The order of the bases in a gene makes up the genetic code. Which gives instructions for the creation of proteins
Protein Synthesis
It occurs in the cytoplasm
Messenger RNA (mRNA) is produced in the nucleus, using DNA as the template
mRNA carries the instructions for the assembly of proteins into the cytoplasm
Proteins are assembled on organelles in the cytoplasm called ribosomes
The number and the sequence of amino acids determines the type of protein and its properties
The sequence of amino acids in the protein is determined by its genetic code
The bases work in threes (base triplets) to code for an amino acid
mRNA is a copy of the base sequence of the DNA that makes up a gene
The mRNA leaves the nucleus and attaches to a ribosome
Transfer RNA (tRNA) ferry amino acids to the ribosome where they are bonded together to form proteins
Switching genes on and off
The cell only produces the proteins it needs to carry out its function
The genes to make these proteins are switched on; the others are switched off
Up to the 8 cell stage of the embryo the cells are the same
The cells produced in the division of embryonic stem cells undergo differentiation to produce specialised cells
Specialised cells begin to make specific proteins. They usually change shape and structure. eg muscle cells must produce the proteins needed to contract
In embryonic stem cells any gene can be switched on so it can produce any type of cell
Embryonic stem cells (and adult stem cells) therefore have the potential to replace cells needed to replace damaged tissues
Stem cell research and therapy
Stem cells are used to produce new cells to replace damaged or diseased cells
Using embryonic stem cells raises ethical issues because in removing cells the embryo is destroyed
According to some, embryos have a right to life from when they're conceived
Embryonic stem cells are normally removed in - in vitro fertilisation
The creation of embryos produced with the intention of destroying them would be even more controversial
Therapeutic cloning
It overcomes some ethical issues of using embryonic stem cells
It involves replacing the nucleus of an egg by the nucleus of a body cell
And stimulating the egg cell to divide to produce an embryo
This technique doesnt require fertilisation and the cells will be genetically identical to the patient so it won't be rejected by the immune system. But the embryo is still destroyed
Using chemical treatment, scientists have managed to transform mammal body cells to stem cell