Def: Disease process that leads to CHD and strokes
(CVDs). Fatty deposits (atheroma) can block arteries
directly or increase possibility of blot clot formation
(thrombosis)
DEVELOPMENT OF ATHEROSCLEROSIS
1) Damage to endothelial lining (artery lining)
Through smoking, high blood
pressure etc
2) Inflammatory response. White blood cells
move into the artery wall
3) Cholesterol build up, leading to atheroma formation
4) Build-up of calcium salts and fibres, leading
to plaque formation
5) Leads to narrowing of artery and loss of
elasticity - hardening of arteries
6) Narrowing of artery leads to increased blood
pressure, so the cycle is never ending
An atheroma is a fatty deposit
HEALTH EFFECTS OF AN ATHEROMA
Increased blood pressure - causes damage
to kidneys and retina, and could cause
strokes
Stroke - an interruption to blood supply of brain,
potentially causing paralysis or death
Aneurysm - increased blood pressure (due to
blockage) could lead to bursting of an artery
and internal bleeding
Angina - chest pain felt during excerise, caused by
reduced blood flow to heart due to narrowing of
coronary arteries
If a coronary artery becomes totally
blocked (by a clot) heart can be starved
of oxygen and die