11.1 Defence Against Infectious Disease

Blood Clotting
1. Clotting Factors
  1. Prothrombin to Thrombin
    1. Fibrinogen to Fibrin
Immunity
1. Natural
  1. Active
  2. Passive
2. Artificial
  1. Active
    1. Vaccination
      1. Challenge: Pathogen
        Specific antibody on B cells bind to pathogen
        Response
        Clonal selection
      2. Beneficials
      3. Dangers
  2. Passive
Antibody production
1. Pathogen
  1. Macrophages eat pathogen
    1. antigen on outer surface of macrophages
      1. Helper T cells matching receptor bind to macrophage
        Memory T cells
        Plasma T cells
        Bind to right B cells
        Plasma B cells
        Antibody production
        Memory B cells
2. Antibody versus antigen
3. Monoclonal antibodies
  1. Antigens into animals
    1. Specific B cells produce antibodies
      1. B cells fuse with tumour cells: hybridoma
        antibody produced and purified
        HCG
        Rabies

Resource summary

	Created by Steve Harton over 10 years ago