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8829295
WBC disorder
Description
Mind Map on WBC disorder, created by Abdulla Nidal on 07/05/2017.
Mind Map by
Abdulla Nidal
, updated more than 1 year ago
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Created by
Abdulla Nidal
over 7 years ago
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Resource summary
WBC disorder
Complications
Infections
Secondary cancers
Anemia
Bleeding disorders
Treatment
Chemotherapy
Terosine kinase inhibitors
first generation
Imatinib
Second generation
Other
Methotrexate
Folic acid
Antimetabolite
Bone marrow transplant
HLA typing
GvH reaction
Investigation
History taking
Ask for
Fatigue, fever, weight loss, discoloration
Blood test
CBC
LAP
Blood film
Other(genetic)
FISH
To see the morphology of chromosome
Karyotype
Sign and symptom
Vast disorders
Fever
Chills
Fatigue
Tenderness and pain
Easy bleeding
Specific
ALL
BM suppression
AML
Chloroma
Gingivitis
CLL
Lymphadenopathy
CML
Huge splenomegaly
Hematopoiesis
Causes
Leukemia
Translocation
Inhibitor of apoptosis
Mutation in Terosine kinase proncogene
Leukocytosis
Infection
Allergy
irritants
Leukopenia
HIV
Autoimmune
Chemo
Pathophysiology
Leukopenia
Neutropenia
Decreased granulocyte production
Will increase risk of bacterial infection
Increased gran. desctruction
Lymphopenia
Not common
Leads to Viral infection
Leukocytosis
Reactive leukocytosis
Neutrophil
Bacteria
Eosinophil
Allergy
Basophil
Rare
Monocyte
Chronic infection
Leukomoid reaction
Mimics leukemia
increased LAP
Leukemia
Lymphoid
Chronic
Most common leukemia
B-cel hyperproliferation
50+ years
Acute
<15 years
Tdt +ve
Lymph adenopathy
Clumped chromatin
Myeloid
Chronic
25-60 years
Extramedullary hematopoeisis
indolent
Acute
Immature blast cells
PAN cytopenia
Lacy chromatin
Media attachments
350px Hematopoietic Growth Factors (image/png)
Acute Leukemia All (image/jpeg)
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