Colibacillosis - septicaemia

E. Coli - septicaemiaPredisposing causes: Colostrum deprivation Highest absorption w/in first 12hrs of birth Rich in antibodies to various serotypes of E. Coli. PASSIVE IMMUNITY! Colostrum quality AgeHighest susceptibility —> birth-day 4 Stress ie nutritional management, env stress Environmental factors Housing calves in the same yards every year Housing calves in dirty muddy yards Housing very young with very old Septicaemic colibacillosisAetiology Disease of poor management; dirty conditions, wet, overcrowded, failure to dip umbilicus Failure of passive transfer Commonly 1-14 days old E. coli may gain entrance through navel, intestine or MM Shed - urine, oral secretions, nasal secretions, later in the faeces Clinical signsSign of overwhelming septicaemia and shock Depression and weakness Complete anorexia Rapid heart rate (>100/minute) Temperature initially high (>40C) Terminally temperature low ( Final stages - diarrhoea Sudden death may be seen Treatment: Often unsuccessful Fluid therapy Antibiotic therapy Ceftiofur 2.2mg/kg IM or SC BID Amoxicillin or ampicillin 10mg/kg IM BID Continue for 3-5 days Flunixin meglumin @ 1.1mg/kg IV or SC SID Whole blood transfusion - maybe