Lincomycins, Polypeptides, Unclassified Antibiotics and Newer Antibiotics

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FlashCards sobre Lincomycins, Polypeptides, Unclassified Antibiotics and Newer Antibiotics, criado por aaudreylynnn em 13-09-2014.
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FlashCards por aaudreylynnn, atualizado more than 1 year ago
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Criado por aaudreylynnn aproximadamente 10 anos atrás
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Resumo de Recurso

Questão Responda
sulfur-containing antibiotics Lincomycins
bacteriostatic / bactericidal - depending on the concentration; binds at 50s; inhibit protein synthesis Lincomycin
structure of Lincomycin HCl contains a basic function, the pyrrolidine nitrogen
side effect of lincomycin pseudomembranous colitis
S/E of clindamycin pseudomembranous colitis
IV or IM when oral administration is not feasible Clindamycin Phosphate
p 315 read
glycopeptide antibiotic S. orientalis Vancomycin HCl
a glycopeptide antibiotic that is a tx for endocarditis by gram positive Vancomycin HCl
a glycopeptide antibiotic that is a tx for endocarditis by gram positive Vancomycin HCl
always IV never IM Vanco
S/E of Vancomycin Ototoxicity, renal damage, phlebitis (inflammation of veins), rashes
a mixture of five closely related glycopeptide antibiotics produced by the actinomycete Actinoplanes teichomyceticus. Teicoplanin
Teicoplanin MOA IM/IV; once a day; impairs bacterial cell wall synthesis less toxic and nephrotoxicity than vancomycin
source of teicoplanin Actinoplanes teichomyceticus
source of bacitracin B. subtilis
it is a complex mixture of polypeptides; bactericidal action is enhanced by zinc; inhibit mucopeptide cell wall synthesis Bacitracin
causes less kidney damage than to others polymyxin B sulfate
source of colistin sulfate Aerobacillus colistinus
forms of colistin (2) sulfate methanesulfonate sulfate - make an oral paediatric suspension methanesulfonate - make IM injection
source of gramicidin brand name Bacillus brevis Kenacomb
components of Tyrothricin gramicidin and tyrocidin
gramicidin - more active component of tyrothricin; ionophone tyrothricin and gramicidin -> gram positive restricted in local applications use
source of chloramphenicol Streptomyces venezuelae
prodrug of chloramphenicol intended for pediatric use. chloramphenicol palmitate
brand name and source of Mupirocin Bactroban; Pseudomonas fluorescens
it is a combination of the streptogramin B quinupristin with the streptogramin A dalfopristin in a 30:70 ratio. brand name Quinupristin/Dalfopristin (Synercid) treatment of serious infections caused by multidrug-resistant Gram-positive organisms such as vancomycin-resistant E. faecium; 2 cods - bactericidal; MOA - 50s; IV
source of Quinupristin/dalfopristin Streptomyces pristinaspiralis
an oxazolidinedione-type antibacterial agent that inhibits bacterial protein synthesis brand name ZyvoxLinezolid (Zyvox)
a first-in-class (a glycylcycline) in- travenous antibiotic Tigecycline (Tygacil)
source of Aztreonam Chromobacterium violaceum
a synthetic 1-beta-methyl carbapenem that is structurally related to beta-lactam antibiotics, particularly the thienamycin group Ertapenem (Invanz, for injection)
orally bioavailable macrolide brandname Telithromycin (Ketek)
source of platensimycin Streptomyces platensis
a new structural class of antibiotics with very po- tent broad-spectrum activity against Gram-positive bacteria. platensimycin

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