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| Questão | Responda |
| Volume of Distribution (Vd) | When the drug is distributed into all of the tissues that it is physically able to penetrate |
| Do water-soluble drugs have low or high Vd? Serum levels? | low Vd; higher serum levels |
| Do lipid-soluble drugs have a high or low Vd? Serum level? | High Vd; lower serum levels |
| If an enzyme is inhibited, the substrate drug is ________ | increased. |
| Name the 3 types of renal excretion | glomerular filtration, tubular secretion, passive tubular reabsorption |
| What factors affect excretion? | pH of urine, overuse of active transport system, enterohepatic recirculation (bile reabsorption reduces excretion) |
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