Rheumatological Drugs

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Pharmacology FlashCards sobre Rheumatological Drugs, criado por Jenna Paterson em 08-10-2020.
Jenna Paterson
FlashCards por Jenna Paterson, atualizado more than 1 year ago
Jenna Paterson
Criado por Jenna Paterson aproximadamente 4 anos atrás
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Resumo de Recurso

Questão Responda
What drug class is allopurinol, and what is it used to treat? Xanthine-oxidase inhibitor - prevents breakdown of purines which produce uric acid. Used to treat gout
What are the side effects of allopurinol? GI upset - diarrhoea
What should you beware of when prescribing azathioprine and allopurinol together? Azathioprine is metabolised into mercaptopurine and therefore its breakdown is slowed down when co-prescribed with allopurinol. It should therefore be replaced with an alternative agent or the dose of azathioprine reduced to take into account the effects of allopurinol on metabolism.
When should allopurinol be given? At least 2 weeks after an acute attack of gout, as it can precipitate acute attacks.

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