Red Blood cells

Questão	Responda
The cellular components of blood are known as the......	formed elements of blood
These include?	Red blood cells White blood cells Platelets (cell fragments involved in blood clotting)
Red Blood Cells account for what percentage of the total blood volume?	45%
In females, the figure is?	around 41%
This value is known as the?	HAEMATOCRIT (blood count)
1 microlitre (1µl) of blood (i.e. 1mm3 of blood) contains:	5 million RBCs in males ~4.5million RBCs in females
Total blood volume is around?	5 litres
Red blood cells are flattened, biconcave discs. They are....um in diameter and....um thick.	7 and 2
The function of RBCs is?	to transport gases in the circulation Oxygen (O2) Carbon Dioxide (CO2)
RBCs have to squeeze through capillaries, so are easily.......	deformable.
Transport of gases is provided by the presence of ................. inside the RBCs	HAEMOGLOBIN
Each RBC contains around............. molecules of Hb	280 million
Hb is a........molecule.	pigment(gives RBCs their colour)
There are TWO main parts to the Hb molecule:	(i) Protein part (globin) pigment part (haem; heme)
Which part contains Iron?	Haem (pigment part)
The haem part carries which gas?	Oxygen
The concentration of Hb in the blood is about .....g/litre	150g
RBCs have few cell organelles. The don't possess?	Nucleus Mitochondria
No mitochondria means?	therefore they obtain energy ANAEROBICALLY (without oxygen)
RBCs have a.....life span.	short
About ...% of the total number of RBCs is destroyed every day	1
The destruction of RBCs occurs in the?	spleen and by phagocytic cells in the circulation
RBC synthesis occurs in the ?	BONE MARROW
In adults , the synthesis occurs in the bone marrow found in?	bones of chest (e.g. sternum) base of skull long bones in arms & legs
large bone marrow cells (stem cells) which DO possess a nucleus go through several cell stages, gradually lose the nucleus and become?	Mature RBCs.
The whole process is under the control of which hormone?	ERYTHROPOIETIN (EPO)
What percentage of EPO comes from the kidneys and what percentage comes from the liver?	90% and 10% Normal circulating levels of EPO maintain the normal rate of RBC synthesis
In situations where there is a decreased level of O2, such as haemorrhage, decreased cardiac efficiency high altitude this stimulates the production of?	EPO therefore stimulates production of extra RBCs therefore increases the oxygen-carrying capacity of the blood

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	Criado por Morgan Morgan quase 11 anos atrás