ROGER’s Painful Toe

Descrição

Mapa Mental sobre ROGER’s Painful Toe, criado por Fatima Alkhateeb em 29-03-2019.
Fatima Alkhateeb
Mapa Mental por Fatima Alkhateeb, atualizado more than 1 year ago
Fatima Alkhateeb
Criado por Fatima Alkhateeb mais de 5 anos atrás
43
0

Resumo de Recurso

ROGER’s Painful Toe
  1. Biochemistry of purine metabolism
    1. DDx of Big Toe Pain
      1. Trauma
        1. Arthritis
          1. Hallux Valgus (Bunion)
            1. Hallux rigidus
            2. Sesamoiditis
            3. Gout
              1. Primary gout (90%)
                1. Overproducation of uric acid
                  1. Decreased excretion of uric acid
                    1. Alcohol consumption
                      1. Renal failure
                      2. Diet (seafood, red meat)
                        1. Fructose containing cyrup
                          1. Chemotherapy, radiotherapy
                        2. Secondary gout (10%)
                          1. Increased cell turnover
                            1. Inborn errors of metabolism
                          2. Pathogenesis
                            1. Risk factors
                              1. Age
                                1. Genetics
                                  1. Obesity
                                    1. Medications
                                      1. Thiazides
                                        1. Low-dose aspirin
                                2. Signs and symptoms
                                  1. Podagra
                                    1. Tophi
                                      1. Swollen inflamed joint
                                    2. Complications
                                      1. Joint deformity
                                        1. Osteoarthritis
                                          1. Renal stones
                                            1. Sinus may be infected
                                3. Pseudogout
                                  1. Deposition of Calcium Pyrophosphate crystals
                                    1. Causes
                                      1. Hyperparathyroidism
                                        1. Hemochromatosis
                                          1. Etidronate disodium therapy
                                            1. Angiography
                                  2. Investigations
                                    1. X-ray
                                      1. CBC
                                        1. Joint aspiration
                                          1. Biochemical tests
                                            1. Uric acid levels
                                              1. BUN levels
                                    2. Management
                                      1. Acute gouty arthritis
                                        1. NSAIDs
                                          1. Corticosteroids
                                            1. Colchicine
                                        2. Hyperuricemia
                                          1. Xanthine oxidase inhibitors
                                            1. Uricoseric drugs
                                              1. Probenecid
                                                1. Pegloticase
                                              2. Allopurinol
                                          2. Prognoisis
                                            1. Treatable with good prognosis if treated directly

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