Antibiotics

Descrição

First Year Dentistry Mapa Mental sobre Antibiotics, criado por sanna pathy em 29-03-2020.
sanna pathy
Mapa Mental por sanna pathy, atualizado more than 1 year ago
sanna pathy
Criado por sanna pathy mais de 4 anos atrás
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Resumo de Recurso

Antibiotics
  1. Cell wall interference
    1. MoA = inhibit cross-linking of peptide chains
      1. Penicillin
        1. Amoxicillin
          1. Broad spectrum
            1. Use
              1. Dento-alveolar infections (with SF/SI)
                1. Bacterial sinusitis
                  1. Prophylaxis (3g, 1hr before)
                    1. After re-implantation of avulsed tooth
                      1. Rapidly progressing Grade C or Unresponsive perio
                        1. 2nd choice
                      2. 500mg, 3xday, 5 days
                      3. Flucloxacillin
                        1. Beta lactamase resistant
                          1. Use
                            1. Soft tissue infections
                              1. Impetigo
                              2. Acute bacterial sialadenitis
                              3. Staph. A
                              4. Co-Amoxiclav
                                1. = Amoxicillin + Clavulanic acid
                                  1. Broad spectrum + Beta lactamase resistant
                                    1. Use
                                      1. 2nd line for dento-alveolar infections
                                        1. Severe dento-alveolar infection with spreading cellulitis
                                          1. Ludwig's Angina
                                    2. Vancomycin
                                      1. Bacitracin
                                      2. Inhibit protein synthesis
                                        1. Tetracylines
                                          1. Doxycline
                                            1. Broad spectrum
                                              1. Anaerobes
                                                1. Use
                                                  1. Rapidly progressing Grade C or Unresponsive perio
                                                    1. If Penicillin allergy
                                                      1. 200mg loading dose + 100mg, 1xday, up to 14 days
                                                  2. Minocycline
                                                    1. MoA = inhibit binding of tRNA at 30S
                                                    2. Gentamycin
                                                      1. MoA = inhibits reading of mRNA at 30S
                                                      2. Macrolides
                                                        1. MoA = inhibition of translocation at 50S
                                                          1. Lincosamides
                                                          2. Clarithromycin
                                                            1. Broad spectrum
                                                              1. Beta-lactamase-producing bacteria
                                                                1. Use
                                                                  1. 2nd line for dentoalveolar infections
                                                                    1. Severe dento-alveolar infection with spreading cellulitis
                                                                  2. Erythromycin
                                                                    1. Azithromycin
                                                                      1. Gram+ve
                                                                        1. Use
                                                                          1. Rapidly progressing Grade C or Unresponsive perio
                                                                            1. 2nd line
                                                                              1. 500mg, 1xday, 3 days
                                                                        2. Chloramphenicol
                                                                          1. MoA = inhibition of transpeptidase (50S)
                                                                          2. Lincosamide
                                                                            1. Clindamycin
                                                                              1. Broad spectrum
                                                                                1. Gram+ve inc. strep. & penicillin-resistant staph.
                                                                                  1. Use
                                                                                    1. 2nd line for dento-alveolar infections
                                                                                      1. 1st choice
                                                                                      2. Severe dento-alveolar infection with spreading cellulitis
                                                                                        1. Ludwig's angina
                                                                                        2. Osteomyelitis
                                                                                        3. Anaerobes
                                                                                          1. 150-300mg, 4xday, 7 days
                                                                                      3. Interfere with Nucleic acids
                                                                                        1. Metronidazole
                                                                                          1. Anaerobes
                                                                                            1. Broad spectrum
                                                                                              1. MoA = inhibits DNA replication
                                                                                                1. Use
                                                                                                  1. Allergy to penicillin
                                                                                                    1. Dentoalveolar infection with SF/SI
                                                                                                      1. 400mg, 3xday, 5 days
                                                                                                      2. Periodontal abscess with SF/SI
                                                                                                        1. 400mg, 3xday, 3 days
                                                                                                        2. NUG
                                                                                                          1. Pericoronitis with SF/SI
                                                                                                            1. Rapidly progressing Grade C or Unresponsive perio
                                                                                                              1. 1st choice
                                                                                                                1. 400mg, 3xday, up to 5 days
                                                                                                            2. Sulfonamides
                                                                                                              1. MoA = inhibits DNA production
                                                                                                              2. Trimethoprim
                                                                                                                1. Rifampicin
                                                                                                                  1. MoA = inhibits RNA synthesis
                                                                                                                    1. Avoid with contraceptive pill

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