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2756334
Muscles
Descrição
Mapa Mental sobre Muscles, criado por ironicmacaroon em 18-05-2015.
Mapa Mental por
ironicmacaroon
, atualizado more than 1 year ago
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Criado por
ironicmacaroon
mais de 9 anos atrás
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Resumo de Recurso
Muscles
Synovial joints
muscles produce force by contraction
therefore you'll require 2 muscles to make a joint move 2 ways
when one muscle contracts, the other must relax
coordination of oppositely pulling muscles
ANTAGONISTIC
joints may be controlled by groups of muscles working together
SYNERGISTS
i.e. elbow
Muscle Types
Cardiac muscle
made of atrial and ventricular muscle
striated
powerful
no fatigue
excitory (conductive), contract feebly but conduct
made of cells in rows, called intercalated disks
form gap junctions, allows free flow of ions
action potential --> v. quick
Involuntary (smooth) muscle
controlled by autonomic nervous system
not striated
single nucleus
contraction is slow
no fatigue
e.g. arterial walls, intestine (peristalsis), iris of eye (circular and radial)
Voluntary (skeletal) muscle
made of myosin and actin
multi-nucleated
made of fibres which are covered by a cell surface membrane
muscle cell cytoplasm = sarcoplasm
many mitocondria and sarcoplasmic reticulum
striated
powerful
but fatigues
myosin is a polypeptide with 2 attachment/binding sites complementary to ATP and actin
Actin is made of 2 types of polypeptide
2 strands of actin (which has myosin binding sites)
Tropomyosin (blocks actin binding site for myosin)
Troponin (binds to Ca2+, actin and tropomyosin)
Sliding Filament Theory
1. Action Potential travels down a motor neurone and triggers release of Ca2+ ions into muscles from sarcoplasmic reticulum
2, Ca2+ combines with troponin
3. Troponin changes shape
4.Troponin pulls tropomyosin off actin, exposing actin binding site for myosin
5. Myosin binds to actin and forms myosin actin crossbridges
6. Myosin pulls the actin over it -- the POWER STROKE
7. Myosin releases the actin and actin returns
ATP is needed to form and break cross bridges
Neuromuscular junctions
1. Action Potential arrives at neuromuscular junction
2.Vesicles containing ACh move and fuse with presynaptic membrane
3. Releases ACh by exocytosis
4. ACh diffuses across neuro muscular junction
5. ACh binds to complementary receptors on postsynaptic membrane
6. t-tubules carry depolarisation deep into the muscle. This causes sarcoplasmic reticulum to release Ca2+
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