Airborne respiratory - Surface
transmissible 2 hrs - Mainly children -
Rare due to vaccination(1 yr and pre
school) - Beware
foreigners/travel/neglect/immunosupressed
- highly infectious and contagious
(-4rash4+)
PRESENATION - Prodrome: Fever,
COryza, Conjunctivitis, Diarrhoea.
Rash: Forehead and neck -
spreads to trunk and legs, flat
erythematous macular rash with
some coalescing. Recovery quick
after rash appearance.
Com;plications -
Bronchopneumonia
(Staph Aureus/Strep
Pneumonia), Otitis Media,
Encephalitis 1/1000 within
2wks of rash appearing
10-15% mortality and 25%
brain damage - Tx
supportive unless
bacterial cause.
CHECK VIT A LEVELS -
LOW VIT A = HIGH
COMPLICATION RISK
RUBELLA AKA GERMAN MEASELS - NOTIFIABLE
RNA RUBIVIRUS TOGAVIRIDAE
- AIRBORNE RESPIRATORY
RSIK - MATERNAL
INFECTION IN EARLY
PREGNANCY =
CONGENITAL RUBELLA
SYNDROME = CARDIAC,
OCULAR, CNS & SKELETAL
COMPLICATIONS
PRESENATION - PRODROME : FEVER, HEADACHE,
ANOREXIA, CONJUNCTIVITS. RASH : PINK DISCRETE
MACULES START AT HEAD SPREAD TO TRUNK
AND LEGS. GENERALISED HEAD
LYMPHADENOPATHY IS CHARACTERISTIC. PETICHAE
ON SOFT PALATE (FORCHHEIMERS SIGN (NOT
DIAGNOSTIC)
INVESTIGATIONS - CLINICAL
DIAGNOSIS IS UNRELAIBLE -
SEROLOGICAL OR SWAB PCR
GOLD STANDARD.
MANAGEMENT - OFF
SCHOOL FOR 7 DAYS AFTER
RASH APPEARANCE -
SUPPORTIVE TX - REST,
FLUIDS, ANTIPYREXIALS -
ASK RE CONTACT WITH
PREGNANT WOMEN
COMPLICATIONS -
ENCEPHALOPATHY
6D POST RASH -
THROMBOCYTOPENIA
- GUILLIANE BARRE
(AUTOIMMUNE MSCL
WKNS, DMG TO
PERIPHERAL N.S.
SCARLET FEVER - NOTIFIABLE
EXOTOXIN MEDIATED FROM
STREPTOCOCCUS PYOGENES
(GROUP A BETA HEAMOLYTIC -
AIRBORNE RESPIRATORY
DROPLETS - SCHOOL EXCLUSION
PREVIOUSLY VERY SERIOUS,
COMPLICATIONS REDUCED
B/C OF ANTIBIOTICS, MAINLY
CHILDREN
PRESENTATION = PRODROME : SORE
THROAT, FEVER, HEADACHE, VOMIT, PAIN -
RASH WITHIN 12-48 HOURS, 1ST - NECK,
CHEST AND SCAPULA THEN SPREADS TO
TRUNK AND LEGS - COARSE SANDPAPER
TEXTURE WITH PINPOINT DARK RED
PUNCTUM ON A DIFUSE ERYTHEMATOUS
BASE - PALE MOUTH, FLUSHED FACE -
EVENTUAL SKIN PEELING - 1ST WHTE
STRAWBERRY TOUNGE THEN RED
STRAWBERRY TONGUE.
INVESTIGATIONS - OFTEN A
CLINICAL DIAGNOSIS -
OTHERWISE THROAT SWAB
AND CULTURE - ENSURE
SWAB TAKEN FROM TONSILS
OR POSTERIOR PHARYNX.
MANAGEMENT - ABX = PENICILLIN
(AZITHROMYCIN IF ALLERGIC) - REST -
FLUIDS - PAIN REFEIF - SCHOOL
EXCLUSION TILL 24HRS POST ABX -
INCREASED RISK TO KIDS WITH
RECENT CHICKEN POX = WATCH FOR
HIGH TEMP, ARTHRITIS OR CELLULITIS.
ABX LOWERS RISK OF RHEUMATIC
FEVER BUT NOT POST STREP
GLOMERULONEPHRITIS
NO ASPIRIN TO
UNDER 16 =
REYES SYNDROME
= LIVER AND
BRAIN DAMAGE
MENINGOCOCCAEMIA - NOTIFIABLE
NEISSERIA MENINGIDITIS - GRAM -VE
DIPLOCOCCUS - NASOPHARANGEAL
COMMENSAL - AIRBORNE RESPIRATORY
SPREAD - MAY PRESENT WITH SEPTIC
ARTHRITIS, OSTEOMYELITIS, CONJUNCTIVITIS,
ENDOPTHALMITIS - PATHOGENIC FORM IS
ENCAPSULATED PREVENTING PHAGOCYTOSIS
VACCINATION OF HIB, MEN C
AND PNEUMOCOCCALS = GROUP
B MOST COMMON - NEW
VACCINE INTRODUCED FOR B IN
2015 MEANS W IS INCREASING -
COMMON IN WINTER/SPRING -
CHILDREN <5 AND 14-19YRS.
PRESENTATION - PRODROME = FEVER,
HEADACHE, LEG PAIN, THIRST,
DIARRHOEA, COLD HANDS AND FEET -
CLASSIC = HAEMORRHAGIC RASH (DONT
WAIT TO ADMIT), NECK STIFFNESS,
PHOTOPHOBIA, BULGING FONTANELLE -
LATE = CONFUSION, SEIZURES,
REDUCED CONSCIOUSNESS
INVESTIGATIONS = BLOOD CULTURES,
FBC, CRP, U&E, RENAL FXN, LFT - PCR
FOR N. MENINGIDITS AND SEROGROUP -
INCREASE IN APTT AND PTT = DIC -
LUMBAR PUNCTURE WHEN STABLE
(MC&S PLUS GLUCOSE AND PCR.
GROUP B STREP = BEN PEN & GENT,
ECOLI = CEFOTAXIME AND GENT,
LISTERIA = AMOX AND GENT
RISK FACTORS -
IMMUNOCOMPROMISED -
STEROID USE - MALIGNANCY
- MILDER FORM WHEN
YOUNGER - DANGEROUS IN
NEONATES AND TO FETUS
IN PREGNANCY - EARLY
PREGNANCY = CONGENITAL
VARICELLA SYNDROME =
GROWTH RESTRICTION,
MICROCEPHALY, CATARACTS -
LATE PREGNANCY =
PREMATURE
DELIVERY/NEONATE CHICKEN
POX (TX IG AND ACICLOVIR)