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343807
Control of gene expression in Prokaryotes
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Advanced Molecular Biology & Biotechnology Mapa Mental sobre Control of gene expression in Prokaryotes, criado por Abbey Roberts em 09-11-2013.
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advanced molecular biology & biotechnology
advanced molecular biology & biotechnology
Mapa Mental por
Abbey Roberts
, atualizado more than 1 year ago
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Criado por
Abbey Roberts
quase 11 anos atrás
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Resumo de Recurso
Control of gene expression in Prokaryotes
Enzymes
Inducible
Constitutive
Repressible
Regulation control
Positive
Negative
Regulatory elements
Cis-acting
Trans-acting
Lac operon
Structural genes
lacZ
lacY
lacA
Negative control
Transcription only occurs when the repressor fails to bind to the operator region
Model
Proved by analysis of lac expression in the absence or presence of lactose in partial diploid merozygotes
Catabolite activating protein
Involved in catabolite repression
repress expression of the lac operon when glucose is present
In the absence of glucose and presence of lactose, CAP exerts positive control
binding the CAP-binding site and facilitating RNA polymerase binding at the promoter
Cyclic adenosine monophosphate is required for CAP binding
Glucose represses expression of adenylyl cyclase
the enzyme that catalyses the production of the trp structural genes
Trp operon
Transcription can occur even when the operon is repressed in the presence of tryptophan
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