The inflammatory myopathies

Descrição

paeds-neurology Mapa Mental sobre The inflammatory myopathies, criado por v.djabatey em 12-01-2014.
v.djabatey
Mapa Mental por v.djabatey, atualizado more than 1 year ago
v.djabatey
Criado por v.djabatey mais de 10 anos atrás
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Resumo de Recurso

The inflammatory myopathies
  1. benign acute myositis
    1. assumed post-viral phenomenon
      1. often follows an upper resp tract infection
        1. runs a self-limiting course
      2. pain & weakness in the affected mm
        1. CPK usually raised
        2. dermatomyositis
          1. systemic illness
            1. probably due to an angiopathy
            2. onset 5-10 years old
              1. acute
                1. typically insidious
                  1. fever
                    1. misery
                      1. eventually symmetrical mm weakness
                        1. mainly proximal
                        2. pharyngeal mm involvement
                          1. swallowing affected
                          2. heliotrope (violaceous) rash
                            1. characteristic
                              1. eyelids
                                1. extensor surfaces of e.g.
                                  1. elbow
                                2. periorbital oedema
                                  1. subcutaneous calcification
                                3. Ix
                                  1. raised ESR, CRP possibly
                                    1. muscle biopsy
                                      1. inflammatory cell infiltrate & atrophy
                                    2. Mx
                                      1. physiotherapy
                                        1. prevent contractures
                                        2. corticosteroids
                                          1. mainstay of Rx
                                            1. continue @ tailored dose for 2 years
                                            2. immunosuppressants
                                              1. methotrexate
                                                1. ciclosporin
                                              2. mortality= 5-10%

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