Stewart Thompson
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Quiz sobre Safe Meds Practice Quiz, criado por Stewart Thompson em 07-10-2017.

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Safe Meds Practice Quiz

Questão 1 de 73

1

What does TGA stand for?

Selecione uma das seguintes:

  • Therapeutic goods association

  • Therapeutic goods administration

  • Therapeutic goods analgesics

  • The Good administration

Explicação

Questão 2 de 73

1

What is the TGA responsible for?

Selecione uma das seguintes:

  • Evaluating, assessing and monitoring therapeutic goods in Australia

  • Prescribing medications to patients

  • Educating patients about the safety of drugs

  • Checking the validity of drug orders

Explicação

Questão 3 de 73

1

Schedule 2 drugs are:

Selecione uma das seguintes:

  • Pharmacist only e.g. panadiene

  • Controlled drugs e.g. morphine

  • Pharmacy medicine e.g. paracetamol

  • Prescription only e.g. antibiotics

Explicação

Questão 4 de 73

1

Schedule 4 drugs are:

Selecione uma das seguintes:

  • Pharmacist only e.g. panadiene

  • Prescription only e.g. antibiotics & hypertensive drugs

  • Controlled drugs e.g. morphine & endone

  • Pharmacy medicine e.g. paracetamol & ibuprofen

Explicação

Questão 5 de 73

1

What are some considerations involved with schedule 8 - controlled drugs? (2 answers)

Selecione uma ou mais das seguintes:

  • Can be administered by 1 RN

  • Are kept in an unlocked cupboard

  • Administration needs 2 RNs

  • Need to be kept in a locked cupboard

Explicação

Questão 6 de 73

1

Generally schedule 3,4 & 8 medication are not advertised in the popular media except inhaled corticosteroids, vaginal anti-infective agents and nicotine to treat smoking dependence.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 7 de 73

1

What are the 6 rights of drug administration?

Selecione uma das seguintes:

  • Right patient, right drug, right dose, right time, right route, right to refuse

  • Right patient, right drug, right time, right dose, right hand, right to restrain

  • Right colour, right flavour, right drug, right dose, right patient, right route

  • Right patient, right drug, right dose, right time, right route

Explicação

Questão 8 de 73

1

Which of the following are necessary for a medication order to be valid? (Pick 5 answers)

Selecione uma ou mais das seguintes:

  • It needs to be dated

  • Is the drug name there?

  • Does NOT need to be legible

  • Signed by a nurse

  • Dose and unit of measurement need to be present

  • Route needs to be documented

  • Signed by a doctor, nurse practitioner or dentist

Explicação

Questão 9 de 73

1

Which answer is not correct regarding roles and responsibilities of the healthcare team when administering drugs?

Selecione uma das seguintes:

  • Doctor can diagnose and prescribe

  • Nurse can Prescribe and dispense

  • Nurse can assess, administer and evaluate

  • Pharmacist can advise and dispense

Explicação

Questão 10 de 73

1

The generic name is also called the trade name, when drug companies market a drug they select a name and copyright it.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 11 de 73

1

The Brand name is the official drug name, approved name given by the manufacturer and local authority.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 12 de 73

1

Enteric coated preparations are not:

Selecione uma das seguintes:

  • designed so disintegration occurs in the intestines rather than the stomach

  • Abbreviated EC on the container

  • to be crushed

Explicação

Questão 13 de 73

1

Capsules can be either Hard gelatine capsules containing a drug as a solid, or soft gelatine capsules which can be opened and are useful for liquids drugs, or those that do not dissolve easily in water

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 14 de 73

1

What type of drug form is released slowly in the GIT and consists of layers of a drug enclosed in successive layers of inert coating?

Selecione uma das seguintes:

  • Controlled release

  • Capsules

  • enteric coated preparations

  • Sustained/slow release

Explicação

Questão 15 de 73

1

what type of drug has a semi permeable membrane coating, and can end up in faeces as a "ghost tablet"

Selecione uma das seguintes:

  • Oral liquids

  • Controlled release tablets

  • topical preparations

  • Enteric coated preparations

Explicação

Questão 16 de 73

1

A nicotine patch would be considered a(n)

Selecione uma das seguintes:

  • oral liquid

  • Topical preparation

  • Capsule

  • Ointment

Explicação

Questão 17 de 73

1

Linctus - is a syrup specially formulated for coughs

Elixers - is an alcoholic solution that is used when the required drug is water insoluble

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 18 de 73

1

Intradermal, subcutaneous, IM, IV, intraarterial & intrathecal are all what forms of administration?

Selecione uma das seguintes:

  • Enteral

  • Parenteral

  • Transdermal

  • Gastro-intestinal

Explicação

Questão 19 de 73

1

Pharmacodynamics is:

Selecione uma das seguintes:

  • What the body does to the drug

  • What the drug does to the body

  • How the drug is altered as it travels through the body

Explicação

Questão 20 de 73

1

Pharmacokinetics is:

Selecione uma das seguintes:

  • What the drug does to the body

  • What the body does to the drug

  • the integration at a molecular level - between the drug molecules and the target cell, receptor where it will stimulate or inhibit the natural chemicals of the body

  • The drugs interaction with structural proteins

Explicação

Questão 21 de 73

1

what is not 1 of the 4 aspects of pharmacokinetics:

Selecione uma das seguintes:

  • Absorption - movement of drug molecules into the body from the site of administration

  • Distribution - the drug enters the bloodstream, and travels to the site of action, will be improved if the drug binds to albumin + globulins in the blood.

  • Disruption to the cellular membrane

  • Metabolism - alters chemical properties of drugs making them less lipophilic (fat soluble) and more readily excreted

  • Excretion - Excreted from the system in various ways e.g. urine, saliva, sweat, tears, breathing

Explicação

Questão 22 de 73

1

Factors affecting;

absorption - chemical nature of the drug, pH of the stomach, Surface area available for absorption & route/solubility of drug

Distribution - lipid solubility

Metabolism - Hepatic 1st pass effect (oral meds)

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 23 de 73

1

What is the term for the fraction of the drug available to the systemic circulation, and is measured on a scale of 0 - 1
(1=100%)

Selecione uma das seguintes:

  • Half life

  • Absorption percentage

  • Bioavailability

  • Hepatic first pass effect

Explicação

Questão 24 de 73

1

Oral meds have a bioavailability of 1 or 100% and IV drugs have a bioavailability of <1

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 25 de 73

1

The following are listed in order of ________ to ________ regarding Rate of absorption

liquids
syrups
parenteral
suspensions
powders
capsules
tablets
coated tablets
enteric coated tablets

Selecione uma das seguintes:

  • Fasted - Slowest

  • Slowest - Fasted

Explicação

Questão 26 de 73

1

Where is the major site of metabolism?

Selecione uma das seguintes:

  • Brain

  • Anus

  • Spleen

  • Liver

Explicação

Questão 27 de 73

1

What is not efficient as a barrier to drugs, and may result in congenital abnormalities?

Selecione uma das seguintes:

  • Blood brain barrier

  • Semipermeable membrane

  • Placental Barrier

  • Swiss cheese model

Explicação

Questão 28 de 73

1

Metabolism occurs in 2 phases

Phase 1 - enzymes modify chemical structure of the drug

Phase 2 - the phase 1 metabolite is joined (conjugated) with another molecule to render the product soluble for excretion

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 29 de 73

1

The hepatic first pass effect

Selecione uma das seguintes:

  • Removes the drug entirely

  • Increased bioavailability

  • Does not remove entire drug but it does reduce the bioavailability

  • recruits the cremaster muscles to aid in the metabolism of drugs

Explicação

Questão 30 de 73

1

The kidneys, GIT as well as saliva, sweat, tears, breath and breast milk are all sites of excretion (drug clearance)

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 31 de 73

1

If the blood concentration of a drug is 1000mg/L at a 12pm, and this level drops to 500mg/L by 4pm. What is the half life?

Selecione uma das seguintes:

  • 2 hours

  • 4 hours

  • 6 hours

  • 8 hours

Explicação

Questão 32 de 73

1

An antihypertensive medication reducing a patients blood pressure too much and causing hypotension would be an example of a drug having:

Selecione uma das seguintes:

  • The correct response

  • Too little response

  • Too much response

  • a nightmare

Explicação

Questão 33 de 73

1

The use of many drugs at once, the use of drugs with no apparent indication, & the duplication of medication taking would indicate _________, which presents a major health care risk to patients

Selecione uma das seguintes:

  • Polydrugs

  • Polydynamesis

  • Polysynthesis

  • Polypharmacy

Explicação

Questão 34 de 73

1

The systems approach to errors identifies that : (pick 3 answers)

Selecione uma ou mais das seguintes:

  • Errors occur just because people are dumb

  • Humans are fallable (capable of making mistakes)

  • Errors are deemed as causes not consequences

  • errors are deemed as consequences not causes

  • Investigations are needed to seek new ways of completing tasks.

Explicação

Questão 35 de 73

1

The Swiss cheese model identifies that there are holes in the layers of defence which include:

Selecione uma das seguintes:

  • Active conditions & Latent failures

  • Active failures & Latent conditions

Explicação

Questão 36 de 73

1

Active failures may lie dormant for some time before combining with a latent condition to create an opportunity for error and if identified they can be remedied before these errors occur (e.g. staffing issues, inexperience or inadequate equipment/training)

Latent conditions are unsafe acts committed by people in direct contact with the patient (e.g. slips, trips, lapses, fumbles, mistakes & procedural violations)

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 37 de 73

1

The ANS (autonomic nervous system) is divided in the Sympathetic nervous system (rest & digest) and the Parasympathetic nervous system (fight or flight).

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 38 de 73

1

The sympathetic nervous system has short pre-ganglionic neurons that release _______ and long post-ganglionic neurons that release _____________ or noradrenaline onto the effector organ. These nerves are adrenergic

Selecione uma das seguintes:

  • Adrenaline - Renin

  • Acetylcholine - Adrenaline

  • Adrenaline - Acetylcholine

  • Renin - Angiotensin II

Explicação

Questão 39 de 73

1

The parasympathetic nervous system has long pre-ganglionic neurons that release ___________ and short post-ganglionic neurons that release ___________ . These nerves are cholinergic

Selecione uma das seguintes:

  • Acetylcholine - Acetylcholine

  • Adrenaline - Adrenaline

  • Adrenaline - Acetylcholine

  • Acetylcholine - Adrenaline

Explicação

Questão 40 de 73

1

The sympathetic nervous system dilates pupils, inhibits flow of saliva, accelerates heartbeat, dilates bronchi, inhibits peristalsis + gastric secretions, coverts glycogen to glucose (glycolysis), releases adrenaline + noradrenaline, and inhibits bladder contractions.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 41 de 73

1

The parasympathetic nervous system stimulates flow of saliva, slows HR, contracts bronchi, stimulates peristalsis + gastric secretions, stimulates release of bile, contracts pupils and contracts the bladder.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 42 de 73

1

Sympatholytics are Agonist drugs that will stimulate and induce the effects of fight or flight

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 43 de 73

1

Sympathomimetics are Antagonist drugs that will inhibit sympathetic stimulation.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 44 de 73

1

Select the adrenergic receptors:

Selecione uma ou mais das seguintes:

  • Nicotinic (responds to stimulation by nicotine, located in smooth + cardiac muscle as well as neuromuscular junction of skeletal muscle)

  • Alpha 1 (abundant on major arteries, associated with vasoconstrictive responses and increased BP)

  • Muscarinic (acetylcholine receptors, acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system.)

  • Beta 2 (abundant on bronchiolar smooth muscle and blood vessels within skeletal muscle, heart, brain and kidneys. Associated with bronchodilation and increased tissue perfusion)

  • Beta 1 (located on myocardium, smooth muscles, GIT sphincters and renal arterioles. Associated with rate/force of heart contraction)

  • Alpha 2 (Abundant on presynaptic terminal, involved with autoregulation of synaptic activity)

Explicação

Questão 45 de 73

1

The roles of ___________ receptors include vasoconstriction (increased BP) , pupil dilation + contraction, urinary retention, glucose release, generalised sweating & GIT constriction (decrease motility).

Selecione uma das seguintes:

  • Alpha 2

  • Alpha 1

  • Beta 1

  • Beta 2

Explicação

Questão 46 de 73

1

The role of __________ receptors are bronchodilation, vasodilation, insulin release and decreased GIT motility.

Selecione uma das seguintes:

  • Alpha 1

  • Alpha 2

  • Beta 1

  • Beta 2

Explicação

Questão 47 de 73

1

The role of _________ receptors are increased HR, increased contractility of the heart, increased atrioventricular conduction, increased renin release and vasoconstriction.

Selecione uma das seguintes:

  • Alpha 1

  • Alpha 2

  • Beta 1

  • Beta 2

Explicação

Questão 48 de 73

1

Alpha 1 ________ drugs would cause ____________ , increased BP, pupil dilation, glucose release, sweating and reduced GIT motility.

Selecione uma das seguintes:

  • Antagonist - vasodilation

  • cholinergic - vasoconstriction

  • agonist - vasoconstriction

  • blocker - vasoconstriction

Explicação

Questão 49 de 73

1

Alpha 1 __________ drugs would cause __________ , reduced BP, pupil constriction, impotence, increased urination and increased GIT motility.

Selecione uma das seguintes:

  • Agonist - vasoconstriction

  • Antagonist - vasoconstriction

  • Antagonist - vasodilation

  • Agonist - vasodilation

Explicação

Questão 50 de 73

1

Alpha 2 agonist drugs can be used to treat ____________

Selecione uma das seguintes:

  • Hypertension

  • Hyperglycaemia

  • Hypothyroidism

  • Diabetes mellitus

Explicação

Questão 51 de 73

1

_________ agonist drugs would increase HR and CO, reduce GIT motility and stimulate the release of renin (increase blood flow and BP)

Selecione uma das seguintes:

  • Alpha 1

  • Alpha 2

  • Beta 1

  • Beta 2

Explicação

Questão 52 de 73

1

Select the incorrect statement from the following regarding phases of clinical trials:

Selecione uma das seguintes:

  • Phase 1 clinical trials involve 20-80 health volunteers

  • Phase 2 clinical trials involve 100-150 volunteers with the targeted illness

  • Phase 3 clinical trials involve 1000-3000 volunteers with the targeted illness

  • Phase 4 clinical trial involves comparisons with other treatments and ongoing safety monitoring whilst out on the market.

  • Phase 1 clinical trials - drugs are tested on individuals from a lower socioeconomic background

Explicação

Questão 53 de 73

1

__________ antagonist drugs (beta blockers) __________ HR, SV, and CO, increase GIT motility and inhibit renin release. Side effects can be dizziness, lethargy, insomnia, diarrhoea, bradycardia and hypotension.

Selecione uma das seguintes:

  • Beta 2 - decrease

  • Alpha 1 - increase

  • Beta 1 - reduce

  • Beta 1 - increase

Explicação

Questão 54 de 73

1

_______ agonist drugs cause _________ , an increase in skeletal muscle excitability (tremors), vasodilation, relaxation of the uterus, reduced bile secretion and increase glycogenolysis.

Selecione uma das seguintes:

  • Beta 1 - vasoconstriction

  • Beta 2 - bronchodilation

  • Beta 1 - bronchodilation

  • Alpha 2 - bronchodilation

Explicação

Questão 55 de 73

1

Ach (acetylcholine) is removed from the synaptic gap by an enzyme called ________________.

Selecione uma das seguintes:

  • Acetylcholinesterase

  • Acetylcholinogen

  • Acetylcholinogenolysis

  • Acetylcholine converting enzyme

Explicação

Questão 56 de 73

1

some side effects of Beta 2 agonist drugs include fine muscle tremors, nervousness, tachycardia, increased BGL + insulin levels and hypokalaemia (low k+)

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 57 de 73

1

Nicotinic agonists increase the feeling of relaxation and well being, also increase skeletal muscle tone (tremors)

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 58 de 73

1

What drug inhibits the breakdown of AcH and therefore enhances the effects of AcH at nicotinic and muscarinic receptors?

Selecione uma das seguintes:

  • Acetylcholinesterase inhibitors

  • Acetylcholinesterase agonists

  • Autocoids

  • Muscarinic agonists

Explicação

Questão 59 de 73

1

I am classed as an autocoid, I am a locally acting substance, I am released and confined to the same tissue and I am found in high concentration in the lungs, skin, GIT and CNS. what am I?

Selecione uma das seguintes:

  • Prostaglandin

  • White blood cell

  • a robot

  • Histamine

Explicação

Questão 60 de 73

1

Histamines are released from ________ and ________ when an allergen, foreign body, or injury is encountered.

Selecione uma das seguintes:

  • G cells - red blood cells

  • enteroendocrine cells - basophils

  • Mast cells - Basophils

  • Sail cells - neutrophils

Explicação

Questão 61 de 73

1

Histamines play a vital role in allergic and inflammatory reactions, some effects can be anaphylaxis, stimulation of pain receptors (nociceptors), vasodilation, and increased capillary permeability (leads to swelling).

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 62 de 73

1

1st generation anti-histamine drugs:

Selecione uma das seguintes:

  • can cross the Blood brain barrier, causing drowsiness and possibly sedation.

  • can only cross the blood brain barrier in small amounts and are therefore not sedating

Explicação

Questão 63 de 73

1

2nd generation anti-histamine drugs:

Selecione uma das seguintes:

  • can only cross the blood brain barrier in small amounts and are therefore not sedating

  • can cross the blood brain barrier, causing drowsiness and sedation

Explicação

Questão 64 de 73

1

___________ can reduce acid stimulation in the stomach so these are beneficial when treating __________ and GORD (gastro - oesophageal reflux disease)

Selecione uma das seguintes:

  • H1 agonists - hypertension

  • H2 antagonists - Peptic ulcers

  • H3 antagonists - peptic ulcers

Explicação

Questão 65 de 73

1

NSAIDs block the synthesis of _____________ by interfering with the ________ and _________ enzymes.

Selecione uma das seguintes:

  • histamines - COX 3 - COX 4

  • Prostaglandins - DIX 1 - DIX 2

  • Prostaglandins - COX 1 - COX 2

  • Histamines - COX 1 - COX 2

Explicação

Questão 66 de 73

1

Regarding Chemical mediator communication which answer is most correct:

Selecione uma das seguintes:

  • Endocrine signalling - molecules travel from signalling cell through the bloodstream to the target cell

  • Paracrine signalling - Signalling cell and the target cell are close together

  • All of these

  • Autocrine signalling - Signalling and target cell are the same cell.

Explicação

Questão 67 de 73

1

all of the following are non-specific COX inhibitors, except:

Selecione uma das seguintes:

  • Aspirin

  • Ibuprofen

  • Diclofenac

  • Celecoxib

  • Indomethicin

Explicação

Questão 68 de 73

1

Prostaglandins do not cause constriction of smooth muscle, vasodilation, aggregation of platelets, increased sensitivity of neurons to pain, the mediation of inflammation, fever (pyrogenic) or the inhibition of acid secretion in the stomach.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 69 de 73

1

Which of the following is not a cardiac medication (antihypertensive)

Selecione uma das seguintes:

  • ACE inhibitors (suffix "pril")

  • Beta blockers (suffix "olol")

  • Calcium channel inhibitors

  • Anti diuretics

  • Loop diuretics

Explicação

Questão 70 de 73

1

The inhibition of COX in peripheral tissue will reduce pain + inflammation. The inhibition of COX in the stomach removes the protective effect of PG (prostaglandin) and results in damage to the GI mucosa.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 71 de 73

1

When a patient is on multiple medications that affect the metabolism, synthesis or uptake of serotonin, what happens to serotonin levels.

Selecione uma das seguintes:

  • Builds up

  • Breaks down

  • No issues

  • Patient gets cooked

Explicação

Questão 72 de 73

1

Serotonin builds up in the neurons of the CNS and it can cause:

Selecione uma das seguintes:

  • A change in mental status

  • Hypertension

  • Hyperpyrexia

  • All of these

  • Ataxia (lack of voluntary coordination of muscle movements)

Explicação

Questão 73 de 73

1

Noradrenaline, adrenaline and dopamine are known as catecholamines

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

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