sterile sites of human body

Human Microbiome Project

conclusions of human microbiome project

How might different microbial communities perform the same functions at a given site?

How to compare two colonies from two different individuals

What areas of the skin can microbes occupy?

different skin environments

P. acnes

oral cavity microenvironments: below the gum line

oral cavity microenvironments: above the gum line

What happens with poor oral hygiene?

Stages of enamel decay

Microbiome of vaginally born babies vs Cesarean section

microbiome pH going down the human gut

alpha diversity

beta diversity

in general, what AFFECTS the GI microbiome?

in general, what is the EFFECT of the GI microbiome?

How do we tolerate billions of commensals?

Experimental evidence of gut microbiome's important role in the immune system

TH17 cells vs Treg cells in segmented filamentous bacteria (SFB)

Gut microbiome link to obesity/metabolic disease: antibiotics and weight gain

Gut microbiome link to metabolic disease: H. pylori and hormones

CHO diet effect on microbiome
(diet --> GI)

Microbiome effect on fat accumulation
(GI --> body)

disbiosis

gnotobiotic mice

Bacteriodes fragillis and Clostridiae in Human Microbiome

effect of human fecal transplant on GF mice

results of cohousing mice with "lean" microbiota and "obese" microbiota (fed on same diet)

results of cohousing mice with "lean" microbiota and "obese" microbiota (fed on different diets)

signaling pathways that most affect metabolic outcomes

What happens when you disturb the GI ecosystem?

treatments for recalcitrant C. difficile

probiotics effect on health