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Apoptosis = cell death
Necrosis = cell death due to injury
Energy-dependent
Only affects necessary cells
Membrane (bubbles form)
condenses
Blebs bud off to break cell up into
Fragments digested by
(mitochondrial) pathway: removal of
growth factors/hormones leads to cascade through mitochondrion, eventually producing (protease enzymes) that disintegrate the and cytoskeleton to cause blebbing
(death-receptor mediated) pathway: death ligand binds to surface receptor to initiate protein cascade that produces caspases
Apoptosis is used in physiological development and ; if cells ordinarily divide, old ones may need to be destroyed
