Module 1 Lecture4 Repair and Regeneration

Patients in the EXCITE trial who demonstrated difficulty grasping were able to perform rapid task performance with the same hand after _______.

How long were the participants post stroke?

How long did the effect of constraint-induced movement thrapy last?

The total number of retrievals ______ while the finger flexions per retrieval _______ after training of the task.

T/F: Motor map is the same across individuals if it's performed accurately.

T/F: once formed, the motor map does not shift anymore.

The monkeys trained in small well food retrieval have _____ digit representation and ______ wrist representation on their motor map.

Reason for losing of wrist representation?

T/F: Digit-wrist shift occured in all animals.

Neurons without blood supply will undergo apoptosis.

Which neurotransmitters/ factors induce apoptosis?

T/F: after post-infarct therapy, the area damaged by the infarct is able to regenerate.

See slide 22. Which synapse is going to weaken/ strengthen?

What is happening at the cortical level during constraint-induced movement therapy?

During Henry Head's self experiment, which sensation returned first, coarse or specific?

Which cell guide and support re-emergence of growth cone?

T/F: nerves that are crushed regenerate faster than nerves that are cut.

__________ remove the myeline debris of damaged nerve.

T/F: newly formed NMJ are at the same location of previous NMJs.

Why is CNS not so good at recovery?

What is the ideal scenario of CNS recovery?

What is the implication of the atomic testing ban study?

Which animal is known to have adult neurogenesis?

T/F: exercise has powerful protective effect on neurons.

T/F: exercise is shown to reduce amyloid-beta expression in Alzheimer's disease.

T/F: Sedentary mice took less time to escape the maze.

Where are the two locations of most evidence of neurogenesis?

Neural precursors generated in the sub ventricular zone move from the ventricle wall along the ________ to the olfactory bulb, where they become ______.

Neuroblasts migrating to the hippocampus differentiate to become _________ neurons.

The neural progenitor cells (also called _______) divide to form neuro______ or ______, and another ________.

How do you educate your patients on neurogenesis?