Biochem - regulation of metabolism in the fed and fasting states

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What is the fed state?

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What happens during the fed state?

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What factors control the flow of intermediates through metabolism?

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When does fasting begin?

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How quickly does the availability of substrates affect the flow of intermediates through metabolism?

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How quickly does the allosteric activators and inhibitors affect the flow of intermediates through metabolism?

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How quickly does the covalent modification of enzymes affect the flow of intermediates through metabolism?

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How quickly does the synthesis of new enzyme molecules affect the flow of intermediates through metabolism?

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The fed state is a ...

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During the fed state nutrients are captured as...

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Glucokinase has a _______ Km for glucose

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How does the liver respond to high blood glucose levels?

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What enzyme phosphorylates glucose?

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Glucose uptake by the hepatocyte __________ rate limiting

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What trasports glucose iinto the liver?

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In the well fed (absorptive state) Glycogen Synthase has a part in one of the major metabolic pathways.
What is glycogen synthase activated by?

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What GLUTs do adipocytes contain?

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Carbohydrate metabolism in the fed state causes.....

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Fat metabolism in the fed state causes...

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In the absorptive state, CHO Metabolism causes ____________ in Skeletal muscle.

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The absorptive state is the same as the fed state

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In the absorptive state, Fat Metabolism causes ____________ in Skeletal muscle.

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In the absorptive state, Amino Acid Metabolism causes ____________ in Skeletal muscle.

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During the absorptive state the grain completely....

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What is the main GLUT used in the brain?

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During the fasting state, plasma levels of glucose, amino acids and TAG fall triggering a ....

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the fasting state is __________

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One of the ❌ priorities during the ❌ state is the need to maintain adequate ❌ levels of ❌ to sustain energy metabolism of the ❌ ❌s and other glucose requiring tissues.

RBC

WBC

2

3

fasting

fed

plasma

blood

glucose

glycogen

brain,

liver

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The other priority in the ❌ state is the need to mobilize ❌ acids from ❌ tissue, and the synthesis and release of ketone bodies from the ❌ to supply ❌ to all other tissues.

fasting

fed

fatty

amino

starchy

adipose

muscle

carbohydrate

liver

kidneys

energy

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Hepatic _________ maintains blood glucose

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Which of these are used in the liver for gluconeogenesis?

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What cycle is important in hepatic gluconeogenesis?

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What cannon be used for NET glucose synthesis?

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What proteins from muscle are important for net glucose synthesis?

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When is the postabsoprtive state?

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What is the early phase of starvation?

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How long does the gluconeogenic phase last?

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When is the period of adaptation to starvation (approx) ?

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During the phase of adaptation to starvation what happens to the active thyroid hormone?

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When does the period of adapted starvation begin?

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Initially during fasting, levels of fatty acids in the blood are...

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During fasting in the liver, fatty acid oxidation provides

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During fasting, when ,Evelyn of ketone bodies (that are released from the liver) are high, they supply the brain, completely replacing glucose

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Ketone bodies prevent...

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During the fasting state the pancreas released...

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Basal energy requirements can be reduced by reducing production of the active thyroid hormone up to

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Late stage fasting occurs after...

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During late stage fasting...

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Which of these occur in the liver in fasting?

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Which of these occur in adipose tissue during fasting?

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Resting muscle uses .... as a fuel source during fasting

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During fasting which of these does exercising muscle use as fuel?

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What becomes the dominant fuel source in muscle during fasting once all other sources are gone?

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In early fasting the brain exclusively uses...

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After 2 weeks of starvation the brain uses ... as a fuel source?

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Which of these are true about the kidney in long term fasting?

Quiz on Biochem - regulation of metabolism in the fed and fasting states, created by Alannah McDonnell on 05/03/2018.

Biochem - regulation of metabolism in the fed and fasting states

What is the fed state?

What happens during the fed state?

What factors control the flow of intermediates through metabolism?

When does fasting begin?

How quickly does the availability of substrates affect the flow of intermediates through metabolism?

How quickly does the allosteric activators and inhibitors affect the flow of intermediates through metabolism?

How quickly does the covalent modification of enzymes affect the flow of intermediates through metabolism?

How quickly does the synthesis of new enzyme molecules affect the flow of intermediates through metabolism?

The fed state is a ...

During the fed state nutrients are captured as...

Glucokinase has a _______ Km for glucose

How does the liver respond to high blood glucose levels?

What enzyme phosphorylates glucose?

Glucose uptake by the hepatocyte __________ rate limiting

What trasports glucose iinto the liver?

In the well fed (absorptive state) Glycogen Synthase has a part in one of the major metabolic pathways. What is glycogen synthase activated by?

What GLUTs do adipocytes contain?

Carbohydrate metabolism in the fed state causes.....

Fat metabolism in the fed state causes...

In the absorptive state, CHO Metabolism causes ____________ in Skeletal muscle.

In the well fed (absorptive state) Glycogen Synthase has a part in one of the major metabolic pathways.
What is glycogen synthase activated by?