What are four characteristics of penicillins?
- strong gram negative coverage - strengthens D-ala/D-ala of the bacterial cell wall - decreased hypersensitivity reactions - binds to transpeptidases
- sensitive to beta lactamases - poor gram negative coverage - decreased risk of hypersensitivity reactions - detaches from transpeptidases
- sensitive to beta lactamases - poor gram negative coverage - binds to transpeptidases - increased risk of hypersensitivity reactions
Which of the following drugs from the penicillin class is vulnerable to beta lactamases?
Penicillin G
Nafcillin
Zosyn
Which antibiotic is specifically indicated in treating Treponema pallidum (syphilis) and injected as a depot?
Mupirocin
Benzathine Penicillin G
Colisitin
Macrolides
The addition of amine groups to a drug will cause:
A decrease in affinity for gram negative cell membranes porins.
A decrease in affinity for gram positive cell membranes porins.
An increase in affinity for gram negative cell membrane porins.
Ticaricillin is useful in treating gram negative bacteria in particular:
Pseudomonas
Anthrax
MRSA
Meningitis
Which of the cephalosporins are useful for treating meningitis?
1st Generation (Cephazolin/Cephalexin)
2nd Generation (Cefuroxime)
3rd Generation (Ceftriaxone)
4th Generation (Cefepime)
5th Generation (Ceftaroline)
Which of the cephalosporins is useful in empiric coverage of nosocomial infections?
Which correct group of drugs may be particularly useful in treating MRSA?
-Rifampin -Clindamycin -Metronidazole -Penicillin G -Vancomycin
-5th Generation Cephalosporin (Ceftaroline) -Vancomycin -Daptomycin -Linezolid -Mupirocin (Bactroban)
-Amoxicillin -Ciprofloxacin -Clindamycin -Gentamicin -Azithromycin
