Large Scale Chromosomal Aberrations

What are the 3 types of chromosome mutations?

On chromosomes, which is the short arm and which is the long arm?

What is aneupolidy?

What are 3 types of aneuploidy?

What are the 4 aneuploids of sex chromosomes? Give 2 examples of conditions that arise from aneuploidy.

How does aneuploidy occur? Give detail of the process.

Give 3 examples of autosomal trisomy and where they occur

What are the 4 types of structural variation of the chromosome?

WHY does structural variation of the chromosome occur?

Give an example for each type of structural variation: deletions and duplications

HOW do structural chromosome variations occur?

How do robertsonian translocations in Down's syndrome occur? What is the frequency of this?

What is the definition of a karyotype?

What are 2 types of variation in the human karyotype?

What is the cause of age-related nondisjunction?