GEGE2001 Week 03 (L05 & L06)

Questão 1 de 15

2

(from end of L05 slides)
In a particular cell, a non Watson-Crick base pair (T-G) is formed during DNA replication. What is likely to happen next?

Selecione uma das seguintes:

Polymerase *probs* removes it, often via 3' exonuclease activity
Polymerase *probs* removes it, often via 5' exonuclease activity
Polymerase *probs* removes it, often via 3' endonuclease activity
Polymerase *probs* removes it, often via 5' endonuclease activity

Explicação

Questão 2 de 15

2

(from end of L05 slides)
How does a frameshift mutation differ from a missense mutation?

Selecione uma das seguintes:

Missense affects many codons; Frameshift mutation does not.
Frameshift affects many codons; Missense mutation does not.
Frameshift affects many codons; Missense mutation only affects 3.
Missense affects many codons; Frameshift mutation only affects 3.

Explicação

Questão 3 de 15

2

(from end of L05 slides)
Did the fluctuation test show that bacterial cells induce mutation upon exposure to the selective agent (viral infection)? Explain. (well, don’t explain here, but be ready to)

Selecione uma das seguintes:

No.
Yes.

Explicação

Questão 4 de 15

1

DNA is replicated in:

Selecione uma das seguintes:

S phase
M phase
G phase
Cytokinesis
Telekinesis

Explicação

Questão 5 de 15

2

UV:

Selecione uma ou mais das seguintes:

light has HIGH energy
light has LOW energy
damage forms a join between two adjacent bases, usually Thymine (forming a Thymine dimer)
damage forms a join between two adjacent bases, usually Cytosine (forming a Cytosine dimer)
damage forms a join between two adjacent bases, usually Adenosine (forming a Adenosine dimer)
damage forms a join between two adjacent bases, usually Guanine (forming a Guanine dimer)
damage forms a join between two adjacent bases, usually Adenine (forming a Adenine dimer)

Explicação

Questão 6 de 15

1

Which of the following is NOT a type of DNA mutation (necessarily)?

Selecione uma ou mais das seguintes:

Indels
Incels
Transitions
Transversions

Explicação

Questão 7 de 15

2

Types of mutations AT THE PROTEIN-CODING LEVEL. Fill in the blanks:
Silent mutation: ❌;
Missense mutation: ❌;
Nonsense mutation: ❌;
Frameshift ❌.

Arraste e solte para completar o texto.

bp change, NO amino acid sequence change

bp change, amino acid change

bp change, early stop codon

1bp+ indel, alters reading frame

Explicação

Questão 8 de 15

1

UV repair in humans is through:

Selecione uma ou mais das seguintes:

Nucleotide excision repair
Enzyme photolyase

Explicação

Questão 9 de 15

1

A mutation resulting in COPY NUMBER VARIATION can vary between identical twins. Therefore it happens during:

Selecione uma das seguintes:

Mitosis
Meiosis
Both of the above
None of the above

Explicação

Questão 10 de 15

1

What does the image above show?

Selecione uma ou mais das seguintes:

Gene expression of different members of a gene family varying in different parts of the same plant
Gene expression of different members of a gene family varying in different stages of the same plant's development

Explicação

Questão 11 de 15

2

(from end of L06 slides)
Variation in gene regulation = mutations that alter the amount of protein product, without a chance in the amino acid sequence. Basically a regulatory mutation. This can be in which of the following:

Selecione uma ou mais das seguintes:

promoters
introns
5’-UTR
3’-UTR
exons
5’-URT
3’-URT

Explicação

Questão 12 de 15

1

Blonde vs brown-hair is an example of variation in:

Selecione uma das seguintes:

gene expression
aa sequence
gene splicing

Explicação

Questão 13 de 15

2

(from end of L06 slides)
Define a gene family:

Selecione uma das seguintes:

A set of several similar genes, formed by duplication of a single original gene
A set of several copies of identical genes, responsible for varying levels of a single trait

Explicação

Questão 14 de 15

1

(from end of L06 slides)
What is a pseudogene?

Selecione uma ou mais das seguintes:

A non-functional copy of a gene including a regulatory mutation that prevents its expression
A non-functional copy of a gene including a premature stop codon within the gene that prevents its expression

Explicação

Questão 15 de 15

2

(from end of L06 slides)
What are the 2 most likely sources of phenotypic and genomic variation between individuals within a species? (…excluding environmental factors for some reason)

Selecione uma ou mais das seguintes:

Variation in amino acid sequences
Regulatory sequences
Variation in gene number
Variation in splicing
Novel genes

	Criado por Michael Jardine mais de 6 anos atrás

L05 - Mutation and repair: - Errors and repair; - Types of mutations; - Consequences of mutation L06 - Mutation and phenotypic variation: - Phenotypic differences can be obtained by: * Adding sequences to the genome; * Changing sequences or gene expression; * Changing the environment

GEGE2001 Week 03 (L05 & L06)

Questão 1 de 15

(from end of L05 slides) In a particular cell, a non Watson-Crick base pair (T-G) is formed during DNA replication. What is likely to happen next?

Selecione uma das seguintes:

Explicação

Questão 2 de 15

(from end of L05 slides) How does a frameshift mutation differ from a missense mutation?

Selecione uma das seguintes:

Explicação

Questão 3 de 15

(from end of L05 slides) Did the fluctuation test show that bacterial cells induce mutation upon exposure to the selective agent (viral infection)? Explain. (well, don’t explain *here*, but be ready to)

Selecione uma das seguintes:

Explicação

Questão 4 de 15

DNA is replicated in:

Selecione uma das seguintes:

Explicação

Questão 5 de 15

UV:

Selecione uma ou mais das seguintes:

Explicação

Questão 6 de 15

Which of the following is NOT a type of DNA mutation (necessarily)?

Selecione uma ou mais das seguintes:

Explicação

Questão 7 de 15

Types of mutations AT THE PROTEIN-CODING LEVEL. Fill in the blanks: Silent mutation: ❌; Missense mutation: ❌; Nonsense mutation: ❌; Frameshift ❌.

Arraste e solte para completar o texto.

Explicação

Questão 8 de 15

UV repair in humans is through:

Selecione uma ou mais das seguintes:

Explicação

Questão 9 de 15

A mutation resulting in COPY NUMBER VARIATION can vary between identical twins. Therefore it happens during:

Selecione uma das seguintes:

Explicação

Questão 10 de 15

What does the image above show?

Selecione uma ou mais das seguintes:

Explicação

Questão 11 de 15

(from end of L06 slides) Variation in gene regulation = mutations that alter the amount of protein product, without a chance in the amino acid sequence. Basically a regulatory mutation. This can be in which of the following:

Selecione uma ou mais das seguintes:

Explicação

Questão 12 de 15

Blonde vs brown-hair is an example of variation in:

Selecione uma das seguintes:

Explicação

Questão 13 de 15

(from end of L06 slides) Define a gene family:

Selecione uma das seguintes:

Explicação

Questão 14 de 15

(from end of L06 slides) What is a pseudogene?

Selecione uma ou mais das seguintes:

Explicação

Questão 15 de 15

(from end of L06 slides) What are the 2 most likely sources of phenotypic and genomic variation between individuals within a species? (…excluding environmental factors for some reason)

Selecione uma ou mais das seguintes:

Explicação

(from end of L05 slides)
In a particular cell, a non Watson-Crick base pair (T-G) is formed during DNA replication. What is likely to happen next?

(from end of L05 slides)
How does a frameshift mutation differ from a missense mutation?

(from end of L05 slides)
Did the fluctuation test show that bacterial cells induce mutation upon exposure to the selective agent (viral infection)? Explain. (well, don’t explain here, but be ready to)

Types of mutations AT THE PROTEIN-CODING LEVEL. Fill in the blanks:
Silent mutation: ❌;
Missense mutation: ❌;
Nonsense mutation: ❌;
Frameshift ❌.

(from end of L06 slides)
Variation in gene regulation = mutations that alter the amount of protein product, without a chance in the amino acid sequence. Basically a regulatory mutation. This can be in which of the following:

(from end of L06 slides)
Define a gene family:

(from end of L06 slides)
What is a pseudogene?

(from end of L06 slides)
What are the 2 most likely sources of phenotypic and genomic variation between individuals within a species? (…excluding environmental factors for some reason)