Physiology III: Excitatory and Inhibitory Neurotransmission in the CNS

Questão 1 de 20

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There is a higher concentration of ( sodium, potassium ) on the outside of the cell and ( potassium, sodium ) inside the cell

Explicação

Questão 2 de 20

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The is a significantly ( higher, lower ) concentration of Calcium extracellularly.

Explicação

Questão 3 de 20

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Na flows inwards, causing ( depolarisation, hyperpolarisation ) which is ( excitatory, inhibitory )
Ca flows inwards, causing ( depolarisation, hyperpolarisation ) which is ( excitatory, inhibitory )
Cl flows inwards, causing ( hyperpolarisation, depolarisation ) which is ( inhibitory, excitatory )
K flows outwards, causing ( hyperpolarisation, depolarisation ) which is ( inhibitory, excitatory )

Explicação

Questão 4 de 20

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Based on the previous question, will a drug that acts as a Na channel antagonist be excitatory or inhibitory?
( Inhibitory, Excitatory, Neither )

Explicação

Questão 5 de 20

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Based on the previous question, will a drug that acts as a Potassium channel antagonist be excitatory or inhibitory?
( Excitatory, Inhibitory )

Explicação

Questão 6 de 20

1

Events at the Synapse are mostly mediated by means of ..

Selecione uma das seguintes:

Calcium Channels
Sodium Channels
Potassium Channels
Chlorine Channels

Explicação

Questão 7 de 20

1

There are two types of receptors upon which neurotransmitters can act.
❌: Direct gating, whereby the receptor is an integral part of the channel it controls
❌: Indirect gating, whereby the receptor and the channel it controls are distinct from one another.

Arraste e solte para completar o texto.

Ionotropic Receptor

Metabotropic Receptor

Synapotropic Receptor

Explicação

Questão 8 de 20

1

Label the receptor types shown in the diagram below.

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Ionotropic Receptors

Synapotropic Receptors

Metabotropic Receptors

Explicação

Questão 9 de 20

1

The major excitatory neurotransmitter is ...

Selecione uma das seguintes:

GABA
Glutamate
Glycine
Dopamine

Explicação

Questão 10 de 20

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However, Glutamate can sometimes also elicit inhibitory effects via ( metabotropic, ionotropic ) glutamate receptors

Explicação

Questão 11 de 20

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Ionotropic Glutamate Receptors:
NMDA receptors mediate ( slow, fast ) excitatory synaptic transmission in the CNS
Non-NMDA receptors mediate ( fast, slow ) excitatory synaptic transmission in the CNS

Explicação

Questão 12 de 20

1

The major inhibitory neurotransmitter is ...

Selecione uma das seguintes:

Glutamine
GABA
Glycine
Dopamine

Explicação

Questão 13 de 20

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As GABA is an inhibitory Neurotransmitter, it tends to mediate which of the following ions.
( Potassium & Chlorine, Potassium & Sodium, Sodium & Chlorine, Sodium & Calcium )

Explicação

Questão 14 de 20

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Ionotropic GABA receptors tend to mediate ( Chlorine channels, Potassium channels )
Metabotropic GABA receptors tend to mediate ( Potassium channels, Chlorine channels )

Explicação

Questão 15 de 20

1

❌ Receptors are faster and act simply as 'on-off' switches for channels

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Ionotropic

Metabotropic

Explicação

Questão 16 de 20

1

❌): Depolarising change in resting membrane potential caused by actions of neurotransmitters.
❌): Hyperpolarising change change in resting potential caused by actions of neurotransmitters.

Arraste e solte para completar o texto.

Excitatory Post-Synaptic Potential (EPSP

Inhibitory Post-Synaptic Potential (IPSP

Explicação

Questão 17 de 20

1

A change in resting membrane potential caused by EPSP or IPSP that is not of sufficient magnitude to cross the threshold for an action potential is called ...

Selecione uma das seguintes:

An Almost There Potential
A Graded Potential
A Median Potential
A Charted Potential

Explicação

Questão 18 de 20

1

Preencha o espaço em branco para completar o texto.

Which neurotransmitter are excitatory neurons most likely to release?

Explicação

Questão 19 de 20

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Neurotransmitters are released in discrete packages called ( Quanta, Bundles, Quota )

Explicação

Questão 20 de 20

1

Label the diagram below relating to cells of the cerebellum.

Arraste a resposta correta para cada ponto laranja.

Mossy Fibre

Granule Cell

Stellate Cell

Purkinje Cell

Basket Cell

Parallel Fibres

Climbing Fibre

	Criado por Matthew Coulson quase 6 anos atrás

Excitatory and Inhibitory Neurotransmission in the CNS given on 4/9/2018

Physiology III: Excitatory and Inhibitory Neurotransmission in the CNS

Questão 1 de 20

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There is a higher concentration of sodium potassium( sodium, potassium ) on the outside of the cell and potassium sodium( potassium, sodium ) inside the cell

Explicação

Questão 2 de 20

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The is a significantly higher lower( higher, lower ) concentration of Calcium extracellularly.

Explicação

Questão 3 de 20

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Explicação

Questão 4 de 20

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Based on the previous question, will a drug that acts as a Na channel antagonist be excitatory or inhibitory? Inhibitory Excitatory Neither( Inhibitory, Excitatory, Neither )

Explicação

Questão 5 de 20

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Based on the previous question, will a drug that acts as a Potassium channel antagonist be excitatory or inhibitory? Excitatory Inhibitory( Excitatory, Inhibitory )

Explicação

Questão 6 de 20

Events at the Synapse are mostly mediated by means of ..

Selecione uma das seguintes:

Explicação

Questão 7 de 20

There are two types of receptors upon which neurotransmitters can act. ❌: Direct gating, whereby the receptor is an integral part of the channel it controls ❌: Indirect gating, whereby the receptor and the channel it controls are distinct from one another.

Arraste e solte para completar o texto.

Explicação

Questão 8 de 20

Label the receptor types shown in the diagram below.

Arraste a resposta correta para cada ponto laranja.

Explicação

Questão 9 de 20

The major excitatory neurotransmitter is ...

Selecione uma das seguintes:

Explicação

Questão 10 de 20

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However, Glutamate can sometimes also elicit inhibitory effects via metabotropic ionotropic( metabotropic, ionotropic ) glutamate receptors

Explicação

Questão 11 de 20

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Ionotropic Glutamate Receptors: NMDA receptors mediate slow fast( slow, fast ) excitatory synaptic transmission in the CNS Non-NMDA receptors mediate fast slow( fast, slow ) excitatory synaptic transmission in the CNS

Explicação

Questão 12 de 20

The major inhibitory neurotransmitter is ...

Selecione uma das seguintes:

Explicação

Questão 13 de 20

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As GABA is an inhibitory Neurotransmitter, it tends to mediate which of the following ions. Potassium & Chlorine Potassium & Sodium Sodium & Chlorine Sodium & Calcium( Potassium & Chlorine, Potassium & Sodium, Sodium & Chlorine, Sodium & Calcium )

Explicação

Questão 14 de 20

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Ionotropic GABA receptors tend to mediate Chlorine channels Potassium channels( Chlorine channels, Potassium channels ) Metabotropic GABA receptors tend to mediate Potassium channels Chlorine channels( Potassium channels, Chlorine channels )

Explicação

Questão 15 de 20

❌ Receptors are faster and act simply as 'on-off' switches for channels

Arraste e solte para completar o texto.

Explicação

Questão 16 de 20

❌): Depolarising change in resting membrane potential caused by actions of neurotransmitters. ❌): Hyperpolarising change change in resting potential caused by actions of neurotransmitters.

Arraste e solte para completar o texto.

Explicação

Questão 17 de 20

A change in resting membrane potential caused by EPSP or IPSP that is not of sufficient magnitude to cross the threshold for an action potential is called ...

Selecione uma das seguintes:

Explicação

Questão 18 de 20

Preencha o espaço em branco para completar o texto.

Which neurotransmitter are excitatory neurons most likely to release?

Explicação

Questão 19 de 20

Selecione da lista do Menu para completar o texto.

Neurotransmitters are released in discrete packages called Quanta Bundles Quota( Quanta, Bundles, Quota )

Explicação

Questão 20 de 20

Label the diagram below relating to cells of the cerebellum.

Arraste a resposta correta para cada ponto laranja.

There is a higher concentration of ( sodium, potassium ) on the outside of the cell and ( potassium, sodium ) inside the cell

The is a significantly ( higher, lower ) concentration of Calcium extracellularly.

Based on the previous question, will a drug that acts as a Na channel antagonist be excitatory or inhibitory?
( Inhibitory, Excitatory, Neither )

Based on the previous question, will a drug that acts as a Potassium channel antagonist be excitatory or inhibitory?
( Excitatory, Inhibitory )

There are two types of receptors upon which neurotransmitters can act.
❌: Direct gating, whereby the receptor is an integral part of the channel it controls
❌: Indirect gating, whereby the receptor and the channel it controls are distinct from one another.

However, Glutamate can sometimes also elicit inhibitory effects via ( metabotropic, ionotropic ) glutamate receptors

Ionotropic Glutamate Receptors:
NMDA receptors mediate ( slow, fast ) excitatory synaptic transmission in the CNS
Non-NMDA receptors mediate ( fast, slow ) excitatory synaptic transmission in the CNS

As GABA is an inhibitory Neurotransmitter, it tends to mediate which of the following ions.
( Potassium & Chlorine, Potassium & Sodium, Sodium & Chlorine, Sodium & Calcium )

Ionotropic GABA receptors tend to mediate ( Chlorine channels, Potassium channels )
Metabotropic GABA receptors tend to mediate ( Potassium channels, Chlorine channels )

❌): Depolarising change in resting membrane potential caused by actions of neurotransmitters.
❌): Hyperpolarising change change in resting potential caused by actions of neurotransmitters.

Neurotransmitters are released in discrete packages called ( Quanta, Bundles, Quota )