Bones

What are the 2 components of the macrostructure of bone?

What are the differences between these 2 types of bone? (4)

What are the 3 main components of bone?

What is the main component of the protein matrix?

What is the function of this organic matrix?

In which disease is there a disorder in the type 1 collagen and therefore results in brittle bones?

What is the name of the mineral component of bone? What is it made up of?

What is the function of the mineral?

What diseases can result from abnormal mineralisation?

What is the difference between them?

In normal people, what proportion of bone is mineralised? How is this different in osteomalacia?

What are the functions of osteoblasts? (2)

Where do osteoblasts originate from?

What is the function of osteoclasts?

How do they do this?

Where do osteoclasts originate from?

What is a characteristic of osteocytes?

What are 3 functions of osteocytes?

What is sclerostin?

Why is there a more sudden decrease in bone mass in post-menopausal women?

What diseases can result from an imbalance between the formation and resorption of bone, and what is the difference between them?

Which hormones play a role in increasing bone density? (3)

Which hormones work to decrease bone density? (3)

What are the 3 stages of fracture healing?