Peripheral Neuropathy, Guillain-Barré Syndrome and Other Common Mononeuropathies

1

In terms of sensory fibres:
❌ facilitate cold perception and pain
❌ facilitate warm perception and pain

Alpha Delta Fibres

C fibres

1

Using the diagram, match the symptoms to their fibre type:
❌ - Weakness, unsteadiness and muscle wasting
❌ - Numbness, paraesthesia and unsteadiness
❌ - Pain and Dyesthesia
❌ - Dizziness, Impotence, Nausea & Vomiting

Large Motor Fibre

Large Sensory Fibre

Small Sensory Fibre

Autonomic Fibre

1

❌: Writhing movements, usually of the fingers, due to abnormal muscle contraction
❌: Writhing movements, usually of the fingers, due to a failure of the neural proprioceptive pathways to the brain

Chorea

Athetosis

Pseudoathetosis

Pseudochorea

1

gait is a condition whereby there is a loss of dorsiflexion when walking resulting in a foot drop and the patient having to lift their foot higher when taking a step to avoid dragging it along the floor.

1

High stepping gait can occur due to damage to which nerve?

1

The graphs in the diagram show different responses to Nerve Conduction Studies.
A: ❌
B: ❌
C: ❌

Normal Nerve Conduction

Axonal Loss

Demyelination

1

Guillain Barre Syndrome is an example of a ( demyelinating, axonal loss ) neuropathy

1

Guillain Barre Syndrome is an acute autoimmune condition whereby autoantibodies attack the ( myelin, soma, axons, dendrites ) of the ( peripheral, central ) nerves

1

Guillain Barre patients progressively develop paraplegia, meaning that they have weakness/paralysis ( from the waist down, in the arms only, in the peripheries (hands & feet) only )

1

Onset of Guillain Barre SYndrome is sometimes associated with infection, mainly by which organism?

1

Typically, what symptom of Guillain Barre tends to present first in patients?

1

Treatment of Guillain Barre Syndrome is typically by Immunoglobulin infusion

1

What is the most common type of hereditary neuropathy?

1

Which four of the following symptoms commonly occur in patients with Charcot-Marie-Tooth disease?

Peripheral Neuropathy, Guillain-Barré Syndrome and Other Common Mononeuropathies lecture given on 18/09/2018

Peripheral Neuropathy, Guillain-Barré Syndrome and Other Common Mononeuropathies

Peripheral Neuropathy, Guillain-Barré Syndrome and Other Common Mononeuropathies

In terms of sensory fibres: ❌ facilitate cold perception and pain ❌ facilitate warm perception and pain

Using the diagram, match the symptoms to their fibre type: ❌ - Weakness, unsteadiness and muscle wasting ❌ - Numbness, paraesthesia and unsteadiness ❌ - Pain and Dyesthesia ❌ - Dizziness, Impotence, Nausea & Vomiting

❌: Writhing movements, usually of the fingers, due to abnormal muscle contraction ❌: Writhing movements, usually of the fingers, due to a failure of the neural proprioceptive pathways to the brain

gait is a condition whereby there is a loss of dorsiflexion when walking resulting in a foot drop and the patient having to lift their foot higher when taking a step to avoid dragging it along the floor.

High stepping gait can occur due to damage to which nerve?

The graphs in the diagram show different responses to Nerve Conduction Studies. A: ❌ B: ❌ C: ❌

Guillain Barre Syndrome is an example of a demyelinating axonal loss( demyelinating, axonal loss ) neuropathy

Guillain Barre Syndrome is an acute autoimmune condition whereby autoantibodies attack the myelin soma axons dendrites( myelin, soma, axons, dendrites ) of the peripheral central( peripheral, central ) nerves

Guillain Barre patients progressively develop paraplegia, meaning that they have weakness/paralysis from the waist down in the arms only in the peripheries (hands & feet) only( from the waist down, in the arms only, in the peripheries (hands & feet) only )

Onset of Guillain Barre SYndrome is sometimes associated with infection, mainly by which organism?

Typically, what symptom of Guillain Barre tends to present first in patients?

Treatment of Guillain Barre Syndrome is typically by Immunoglobulin infusion

What is the most common type of hereditary neuropathy?

Which four of the following symptoms commonly occur in patients with Charcot-Marie-Tooth disease?

In terms of sensory fibres:
❌ facilitate cold perception and pain
❌ facilitate warm perception and pain

Using the diagram, match the symptoms to their fibre type:
❌ - Weakness, unsteadiness and muscle wasting
❌ - Numbness, paraesthesia and unsteadiness
❌ - Pain and Dyesthesia
❌ - Dizziness, Impotence, Nausea & Vomiting

❌: Writhing movements, usually of the fingers, due to abnormal muscle contraction
❌: Writhing movements, usually of the fingers, due to a failure of the neural proprioceptive pathways to the brain

The graphs in the diagram show different responses to Nerve Conduction Studies.
A: ❌
B: ❌
C: ❌

Guillain Barre Syndrome is an example of a ( demyelinating, axonal loss ) neuropathy

Guillain Barre Syndrome is an acute autoimmune condition whereby autoantibodies attack the ( myelin, soma, axons, dendrites ) of the ( peripheral, central ) nerves

Guillain Barre patients progressively develop paraplegia, meaning that they have weakness/paralysis ( from the waist down, in the arms only, in the peripheries (hands & feet) only )