Matthew Coulson
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Disorders of the Neuromuscular Junction & Muscle given on 26/09/2018

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Matthew Coulson
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Disorders of the Neuromuscular Junction & Muscle

Questão 1 de 14

1

Lambert Eaton Myasthenic Syndrome is a autoimmune disease whereby antibodies attack and destroy ...

Selecione uma das seguintes:

  • Presynaptic Vesicles

  • Presynaptic Calcium Channels

  • Postsynaptic Receptors

Explicação

Questão 2 de 14

1

Lambert Eaton Myasthenic Syndrome typically causes muscle weakness in which parts of the body?

Selecione uma das seguintes:

  • Distal limbs (arms and legs)

  • Proximal limbs (arms and legs)

  • Typically legs only

  • Typically arms only

Explicação

Questão 3 de 14

1

60% of patients with Lambert-Eaton Myasthenic Syndrome have an underlying malignancy. Which malignancy does it most commonly present with?

Selecione uma das seguintes:

  • Small cell lung cancer

  • Adenocarcinoma of the lung

  • Squamous cell lung cancer

  • Large cell lung cancer

  • Breast cancer

  • Renal cancer

Explicação

Questão 4 de 14

1

What is the most common disorder of the neuromuscular junction?

Selecione uma das seguintes:

  • Lambert-Eaton Myasthenic Syndrome

  • Myasthenia Gravis

  • Neuromyotonia

  • Congenital Myasthenia

Explicação

Questão 5 de 14

1

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Myasthenia Gravis is an autoimmune condition whereby the body develops autoantibodies against receptors

Explicação

Questão 6 de 14

1

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Symptoms of Myasthenia Gravis only tend to start once ACh receptors are reduced to ( 30, 60, 5 )% of normal

Explicação

Questão 7 de 14

1

Which of the following structures is also known to play a part in Myasthenia Gravis?

Selecione uma das seguintes:

  • Thymus

  • Bone Marrow

  • Thalamus

  • Pituitary Gland

  • Adrenal Gland

Explicação

Questão 8 de 14

1

Males tend to typically present with Myasthenia Gravis in their 30s whereas woman tend to present in their 60s-70s

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 9 de 14

1

The difference between Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome is that ...

Selecione uma das seguintes:

  • Myasthenia Gravis tends to present mostly in the proximal legs, but not the arms.

  • Myasthenia Gravis tends to present mostly in the proximal arms, but not the legs.

Explicação

Questão 10 de 14

1

Whilst Myasthenia Gravis typically presents with proximal weakness of the proximal leg muscles, it also tends to cause weakness in which of the following?

Selecione uma ou mais das seguintes:

  • Extraocular muscles

  • Facial muscles

  • Carpal muscles

  • Tarsal muscles

  • Abdominal muscles

  • Investing fascia muscles

Explicação

Questão 11 de 14

1

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The initial therapy for most patients with myasthenia gravis is an oral acetylcholinesterase inhibitor, usually ( Pyridostigmine, Physostigmine, Neostigmine, Rivastigmine )

Explicação

Questão 12 de 14

1

Aminoglycoside antibiotics impair neuromuscular transmission and can cause clinically significant muscle weakness, resulting in respiratory depression in myasthenia gravis patients.
Therefore, which of the following medications should be avoided in such patients?

Selecione uma das seguintes:

  • Gentamicin

  • Ceftriaxone

  • Amoxicillin

  • Metronidazole

  • Doxycycline

Explicação

Questão 13 de 14

1

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Inability to relax voluntary muscle after vigorous effort is known as .

Explicação

Questão 14 de 14

1

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Rhabdomyolysis releases high amounts of into the plasma thus causing Acute Kidney Injury (AKI)

Explicação