Kathleen Jackson
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EoT Exam Module 5 & 6

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Kathleen Jackson
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2808NRS Human Pathophysiology and Pharmacology 2 (Module 5 & 6)

Questão 1 de 76

1

The tendency to involuntarily pass urine, usually in small amounts, when abdominal pressure is raised during coughing, for example, is termed:

Selecione uma das seguintes:

  • urge incontinence

  • neurological incontinence

  • stress incontinence

  • overflow incontinence

Explicação

Questão 2 de 76

1

Which diuretics promote the greatest diuresis?

Selecione uma das seguintes:

  • Thiazides.

  • Potassium-sparing diuretics.

  • Aldosterone inhibitors.

  • Loop diurectics.

Explicação

Questão 3 de 76

1

Turbid urine normally indicates:

Selecione uma das seguintes:

  • kidney stones

  • diabetes

  • infection

  • dehydration

Explicação

Questão 4 de 76

1

Which is most likely to contribute to overflow incontinence?

Selecione uma das seguintes:

  • kidney stones lodged in the renal calyxes

  • glomerulonephritis

  • prostate enlargement

  • urethritis

Explicação

Questão 5 de 76

1

Azotaemia describes increased concentrations of:

Selecione uma das seguintes:

  • nitrogen waste compounds in blood

  • urea in urine

  • potassium and sodium levels in blood

  • azotaemia is, in fact, an alternative term for uraemic frost

Explicação

Questão 6 de 76

1

From the following, choose the substance likely to appear in the urine when the glomerulus is inflamed.

Selecione uma das seguintes:

  • Creatinine

  • Urea

  • Sodium

  • Albumin

Explicação

Questão 7 de 76

1

When comparing normal kidney function with dialysis, which of the following mechanisms is not possible in dialysis?

Selecione uma das seguintes:

  • Diffusion

  • Active transport

  • Ultrafiltration

  • Osmosis

Explicação

Questão 8 de 76

1

Which of the following should be present in the filtrate in the proximal convoluted tubule?

Selecione uma das seguintes:

  • Erythrocytes

  • Leukocytes

  • Glucose molecules

  • Plasma proteins

Explicação

Questão 9 de 76

1

Common causes of urolithiasis include all of the following EXCEPT:

Selecione uma das seguintes:

  • hypercalcemia.

  • hyperlipidemia.

  • inadequate fluid intake.

  • hyperuricemia.

Explicação

Questão 10 de 76

1

Which of the following increases glomerular filtration rate?

Selecione uma das seguintes:

  • Constriction of the afferent arteriole

  • Increased hydrostatic pressure in the glomerular capillaries

  • Dilation of the efferent arteriole

  • Increased plasma osmotic pressure

Explicação

Questão 11 de 76

1

Reducing fluid intake is non-pharmacological advice designed to decrease the incidence of urinary tract infections.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 12 de 76

1

Infection and inflammation of the bladder is termed:

Selecione uma das seguintes:

  • cystitis

  • urethritis

  • pyelonephritis

  • any of the above, depending on the origin of the infection

Explicação

Questão 13 de 76

1

The incidence of urinary tract infections is about the same in women and in men, but treatment is more frequently sought by women.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 14 de 76

1

Requesting patients to produce a mid-stream urine sample is designed to ensure the sample is not diluted by urine that has accumulated at the base of the bladder and in the urethra.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 15 de 76

1

Under normal circumstances urine in the bladder is sterile, but it may be contaminated with bacteria upon exiting the urethra.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 16 de 76

1

What is the cause of most cases of pyelonephritis?

Selecione uma das seguintes:

  • Severe pH imbalance of urine

  • Dialysis or other invasive procedure

  • An ascending infection by E. coli

  • Abnormal immune response, causing inflammation

Explicação

Questão 17 de 76

1

What is the first indicator in the arterial blood gases of acidosis caused by glomerulonephritis?

Selecione uma das seguintes:

  • Increased carbonic acid

  • Increased bicarbonate ion

  • Decreased bicarbonate ion

  • A pH less than 7.35

Explicação

Questão 18 de 76

1

Which of the following would be considered normal serum pH?

Selecione uma das seguintes:

  • 7.0

  • 7.4

  • 8

  • 4.5 - 8

Explicação

Questão 19 de 76

1

In a case of acute pyelonephritis, what is the cause of flank pain?

Selecione uma das seguintes:

  • Increasing glomerular permeability, creating an increased volume of filtrate in the kidney

  • Inflammation, causing ischemia in the tubules

  • Inflammation, stretching the renal capsule

  • Microbes irritating the tissues

Explicação

Questão 20 de 76

1

Pyelonephritis may be distinguished from cystitis by the presence in pyelonephritis of:

Selecione uma das seguintes:

  • urinary casts and flank pain.

  • painful micturition.

  • microbes, leukocytes, and pus in the urine.

  • urgency and frequency.

Explicação

Questão 21 de 76

1

An elderly male patient produced only 25 mL of urine in the past 24 hours. The urologist discovers that prostatic hypertrophy is the cause. Which one of the following best describes this patient's acute renal failure?

Selecione uma das seguintes:

  • Postrenal oliguric

  • Prerenal anuric

  • Postrenal anuric

  • Intrinsic nonoliguric

Explicação

Questão 22 de 76

1

Which one of the following electrolytes usually must be restricted in patients with acute renal failure?

Selecione uma das seguintes:

  • Potassium

  • Bicarbonate

  • Calcium

  • Chloride

Explicação

Questão 23 de 76

1

Intrinsic acute kidney injury can be identified/caused by?

Selecione uma das seguintes:

  • decreased creatinine

  • a blockage of the renal artery

  • glomerulonephritis

  • haemorrhage

Explicação

Questão 24 de 76

1

What is the definition of acute kidney injury?

Selecione uma das seguintes:

  • A drop in serum creatinine to less than or equal to 26 umol/L within 48 hours.

  • An increase in urine output to greater than 0.5 mL/kg/hr for 6 consecutive hours.

  • A rise in serum creatinine to greater than or equal to 26 umol/L within 48 hours.

  • An decrease in urine output to greater than 0.5 mL/kg/hr for 6 consecutive hours.

Explicação

Questão 25 de 76

1

Which of the following indicates the early stage of acute renal failure?

Selecione uma das seguintes:

  • Very low GFR and increased serum urea

  • Hypotension and increased urine output

  • Development of decompensated acidosis

  • Polyuria with urine of fixed and low specific gravity

Explicação

Questão 26 de 76

1

What is/are a cause(s) of acute tubule necrosis and acute renal failure?

Selecione uma das seguintes:

  • Sudden significant exposure to nephrotoxins

  • Prolonged circulatory shock

  • Crush injuries or burns

  • All of the above

Explicação

Questão 27 de 76

1

What is the primary reason for hypocalcemia developing during end-stage renal failure or uremia?

Selecione uma das seguintes:

  • Insufficient calcium in the diet

  • A deficit of activated vitamin D and hyperphosphatemia

  • Excessive excretion of calcium ions in the urine

  • Decreased parathyroid hormone secretion

Explicação

Questão 28 de 76

1

Which of the following would likely cause chronic renal failure?

Selecione uma das seguintes:

  • Circulatory shock

  • Diabetes mellitus

  • Cystitis with pyelonephritis in the right kidney

  • Obstruction of a ureter by a renal calculus

Explicação

Questão 29 de 76

1

What causes polyuria during the stage of renal insufficiency?

Selecione uma das seguintes:

  • Loss of tubule function

  • Increased GFR

  • Increased blood pressure

  • Decreased aldosterone secretion

Explicação

Questão 30 de 76

1

Insensible water loss occurs from ________, and ________.

Selecione uma das seguintes:

  • irregular incidents, such as vomiting as output can vary greatly

  • faeces; accounts for approximately 15% of normal daily output

  • kidneys; accounts for approximately 35% of normal daily output

  • lungs and skin; accounts for approximately 30% of normal daily output

Explicação

Questão 31 de 76

1

Fluid load in patients may be increased, inadvertently or purposely, by:

Selecione uma das seguintes:

  • rectal solutions

  • enteral feeding

  • peritoneal dialysis

  • all of the above

Explicação

Questão 32 de 76

1

Which condition will induce cell shrinking?

Selecione uma das seguintes:

  • when interstitial fluid is hypertonic

  • when interstitial fluid is hypotonic

  • when interstitial fluid is isotonic

  • all of the above

Explicação

Questão 33 de 76

1

An athlete who has lost a litre or more of fluid via sweating is best advised to replace this with a solution that contains both salts and water, and a total osmolarity of approximately:

Selecione uma das seguintes:

  • 5.8 mOsmols

  • 90 mOsmols

  • 280 mOsmols

  • 560 mOsmols

Explicação

Questão 34 de 76

1

A clinical use of a hypertonic solution is:

Selecione uma das seguintes:

  • To correct whole blood loss with mild hypvolaemia

  • Dehydrated patients with severe hypernatremia

  • Treat severe intracellular dehydration

  • Treating cerebral oedema and intracranial hypertension

Explicação

Questão 35 de 76

1

Which of the following is an example of an isotonic solution?

Selecione uma das seguintes:

  • 0.45% sodium chloride.

  • 4% glucose with 0.18% sodium chloride.

  • 10% glucose.

  • 25% mannitol.

Explicação

Questão 36 de 76

1

Which of the following is an example of an hypotonic solution?

Selecione uma das seguintes:

  • 0.9% sodium chloride

  • 25% mannitol

  • Water

  • Whole blood

Explicação

Questão 37 de 76

1

A 70-year-old male with chronic renal failure presents with oedema. Which of the following is the most likely cause of this condition?

Selecione uma das seguintes:

  • increased interstitial oncotic pressure

  • decreased capillary oncotic pressure

  • increased capillary oncotic pressure

  • decreased capillary hydrostatic pressure

Explicação

Questão 38 de 76

1

A 10-year-old male is brought to the ED because he is incoherent and semiconscious. CT scan reveals he is suffering from cerebral oedema. This type of oedema is referred to as:

Selecione uma das seguintes:

  • pitting oedema

  • localised oedema

  • generalised oedema

  • pulmonary oedema

Explicação

Questão 39 de 76

1

Insensible fluid loss refers to water lost through:

Selecione uma das seguintes:

  • faeces only

  • perspiration only

  • urine and faeces

  • perspiration and expiration

Explicação

Questão 40 de 76

1

A 35-year-old male weighs 70 kg. Approximately how much of this weight is intracellular fluid?

Selecione uma das seguintes:

  • 5 L

  • 10 L

  • 28 L

  • 42 L

Explicação

Questão 41 de 76

1

A 5-year-old male presents to the ED with delirium and sunken eyes. After diagnosing him with severe dehydration, the doctor orders fluid replacement. The nurse administers a hypertonic IV solution. Which of the following would be expected?

Selecione uma das seguintes:

  • his symptoms would subside quickly

  • decreased extracellular fluid volume

  • intracellular dehydration

  • increased intracellular fluid volume

Explicação

Questão 42 de 76

1

Which of the following is a common cause of hyponatraemia?

Selecione uma das seguintes:

  • Prolonged period of rapid, deep respirations

  • Excessive sweating

  • Loss of the thirst mechanism

  • Excessive aldosterone secretion

Explicação

Questão 43 de 76

1

Which of the following ions is most closely related to water movement?

Selecione uma das seguintes:

  • Potassium

  • Sodium

  • Chloride

  • Calcium

Explicação

Questão 44 de 76

1

Which of the following is the primary cation in the extracellular fluid?

Selecione uma das seguintes:

  • Bicarbonate

  • Potassium

  • Chloride

  • Sodium

Explicação

Questão 45 de 76

1

Which compartment contains the greatest amount of body water

Selecione uma das seguintes:

  • Intracellular

  • Interstital

  • Plasma

  • Transcellular

Explicação

Questão 46 de 76

1

When a patient is being treated with thiazide diuretics, there is a danger of ________, an unwanted and potentially dangerous side effect.

Selecione uma das seguintes:

  • hypocalcaemia

  • hypokalaemia

  • hypophosphataemia

  • hyponatraemia

Explicação

Questão 47 de 76

1

Hyperkalaemia causes:

Selecione uma das seguintes:

  • a decrease in resting membrane potential with increased excitability of cardiac muscle.

  • a decrease in resting membrane potential with decreased excitability of cardiac muscle.

  • an increase in resting membrane potential with decreased excitability of cardiac muscle.

  • an increase in resting membrane potential with increased excitability of cardiac muscle.

Explicação

Questão 48 de 76

1

Which of the following would most likely cause hypochloraemia?

Selecione uma das seguintes:

  • hypokalaemia

  • hypernataemia

  • elevated bicarbonate

  • hypercalcaemia

Explicação

Questão 49 de 76

1

A 42-year-old female presents to her GP complaining of muscle weakness and cardiac abnormalities. Laboratory tests indicate that she is hypokalaemic. Which of the following could be the cause of her condition?

Selecione uma das seguintes:

  • hypoglycaemia

  • respiratory acidosis

  • constipation

  • frusemide therapy

Explicação

Questão 50 de 76

1

Secretion of aldosterone results in:

Selecione uma das seguintes:

  • decreased plasma osmolality.

  • increased blood volume.

  • increased serum potassium levels.

  • localised oedema.

Explicação

Questão 51 de 76

1

Metabolic acidosis may be associated with

Selecione uma das seguintes:

  • Increased chloride levels

  • Decreased bicarbonate

  • Increased metabolic acids

  • All answers are correct

Explicação

Questão 52 de 76

1

Chronic compensation for respiratory acidosis includes:

Selecione uma das seguintes:

  • kidney excretion of HCO3-

  • kidney excretion of H+

  • protein buffering

  • prolonged exhalations to blow off CO2

Explicação

Questão 53 de 76

1

Which of the following is a strong acid?

Selecione uma das seguintes:

  • Phosphorus

  • Albumin

  • Sodium chloride

  • Lactate

Explicação

Questão 54 de 76

1

Long-term regulation of acid-base balance through removal or retention of acids is accomplished by the:

Selecione uma das seguintes:

  • lungs

  • kidneys

  • liver

  • protein buffer systems

Explicação

Questão 55 de 76

1

Which of the following buffer pairs is considered the major plasma buffering system?

Selecione uma das seguintes:

  • NH3/NH4

  • NaCl/KPO4

  • HCO3-/H2CO3

  • HPO4/H2PO4

Explicação

Questão 56 de 76

1

Autoregulation in the kidneys refers to:

Selecione uma das seguintes:

  • the control of systemic blood pressure by the kidneys.

  • control of blood flow by the SNS.

  • the secretion of renin and activation of angiotensin.

  • local minor reflex adjustments in the arterioles to maintain normal blood flow.

Explicação

Questão 57 de 76

1

Place the following events in the correct sequence of events when ketoacids increase in the blood of a diabetic patient.
Not all options are used in the answers.
1. Serum pH decreases
2. Serum bicarbonate decreases
3. PCO2 decreases
4. Respiration decreases
5. Respiration increases
6. Serum pH increases
7. Serum bicarbonate increases

Selecione uma das seguintes:

  • 7, 6, 5, 3, 6

  • 2, 6, 5, 3, 7

  • 7, 6, 4, 3, 1

  • 2, 1, 5, 3, 6

Explicação

Questão 58 de 76

1

Which condition is likely to cause metabolic acidosis?

Selecione uma das seguintes:

  • Slow, shallow respirations

  • Excessive fluid in the body

  • Prolonged diarrhoea

  • Mild vomiting

Explicação

Questão 59 de 76

1

A 55-year-old female presents to her GP complaining of dizziness, confusion and tingling in the extremities. Blood tests reveal an elevated pH, decreased PCO2 and slightly decreased HCO3-. Which of the following is the most likely diagnosis?

Selecione uma das seguintes:

  • respiratory alkalosis with renal compensation

  • respiratory acidosis with renal compensation

  • metabolic alkalosis with respiratory compensation

  • metabolic acidosis with respiratory compensation

Explicação

Questão 60 de 76

1

Which serum value indicates decompensated metabolic acidosis?

Selecione uma das seguintes:

  • Bicarbonate level increases

  • Bicarbonate level decreases

  • pH is above normal range

  • pH is below normal range

Explicação

Questão 61 de 76

1

Acute compensation for metabolic acidosis includes:

Selecione uma das seguintes:

  • CO2 retention.

  • kidney excretion of H+.

  • hyperventilation.

  • hypoventilation.

Explicação

Questão 62 de 76

1

A 52-year-old male with diabetes presents to the ED with lethargy, confusion and depressed reflexes. His wife indicates that he does not follow the prescribed diet and takes his medication sporadically. Which of the following is most likely to occur?

Selecione uma das seguintes:

  • diabetes insipidus

  • decreased extracellular fluid osmolality

  • hyponatraemia

  • decreased urine formation

Explicação

Questão 63 de 76

1

Uncontrolled essential hypertension may cause chronic renal failure because of:

Selecione uma das seguintes:

  • damage to afferent arterioles and renal ischemia.

  • failure of tubules to respond to hormonal controls.

  • glomerular congestion causes damaged capillaries.

  • predisposition to recurrent urinary tract infections.

Explicação

Questão 64 de 76

1

In chronic renal failure, which of the following is the most immediately dangerous?

Selecione uma das seguintes:

  • acidosis

  • phosphataemia

  • haematuria

  • anaemia

Explicação

Questão 65 de 76

1

Which of the following causes acute renal failure?

Selecione uma das seguintes:

  • Nephrosclerosis

  • Bilateral acute glomerulonephritis

  • Polycystic kidney disease

  • Pyelonephritis in the right kidney

Explicação

Questão 66 de 76

1

Which of the following is a typical sign of dehydration?

Selecione uma das seguintes:

  • Rapid, strong pulse

  • Low haematocrit

  • Increased urine output

  • Decreased tissue turgor

Explicação

Questão 67 de 76

1

The normal pH of urine is:

Selecione uma das seguintes:

  • 1.5-5.5.

  • 4.5- 8.0.

  • 7.35-7.45.

  • 7.0-10.

Explicação

Questão 68 de 76

1

Which of the following conditions would decrease oncotic pressure in the capillaries?

Selecione uma das seguintes:

  • low blood pressure

  • high-protein diet

  • liver failure

  • high blood-glucose

Explicação

Questão 69 de 76

1

Chronic renal failure adversely affects which body system?

Selecione uma das seguintes:

  • the cardiovascular system

  • the respiratory system

  • the CNS

  • All answers are correct

Explicação

Questão 70 de 76

1

Infants are at a higher risk for developing dehydration because they have:

Selecione uma das seguintes:

  • a lower total body water volume.

  • a decreased intravascular volume.

  • a greater body surface area.

  • an increased tendency towards developing oedema.

Explicação

Questão 71 de 76

1

Which of the following would result in hyperkalaemia?

Selecione uma das seguintes:

  • insulin

  • excess aldosterone

  • acute acidosis

  • alkalosis

Explicação

Questão 72 de 76

1

Which of the following results from decreased blood flow into the kidneys?

Selecione uma das seguintes:

  • Systemic blood pressure drop

  • Dilation of the afferent arterioles

  • Increased angiotensin and systemic vasoconstriction

  • Decreased aldosterone secretion

Explicação

Questão 73 de 76

1

Which of the following alterations would result in fluid movement into the interstitial space?

Selecione uma das seguintes:

  • increased interstitial hydrostatic pressure

  • decreased capillary hydrostatic pressure

  • increased capillary oncotic pressure

  • decreased capillary oncotic pressure

Explicação

Questão 74 de 76

1

Causes of respiratory acidosis include:

Selecione uma das seguintes:

  • hyperventilation.

  • an increase in noncarbonic acids.

  • pneumonia.

  • vomiting.

Explicação

Questão 75 de 76

1

Crush injuries associated with a massive degree of cell rupture are likely to increase levels of extracellular:

Selecione uma das seguintes:

  • potassium

  • calcium

  • sodium

  • phosphate

Explicação

Questão 76 de 76

1

Choose the basic cause of bone remodelling disorders associated with chronic renal failure.

Selecione uma das seguintes:

  • Excessive loss of phosphate ion

  • Deficit of parathyroid hormone

  • Failure of the kidney to activate vitamin D

  • Development of hypercalcemia

Explicação