Matthew Coulson
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Neurobiology of Addiction lecture given on 05/10/2018

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Matthew Coulson
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Neurobiology of Addiction

Neurobiology of Addiction

Questão 1 de 9

1

Preencha os espaços em branco para completar o texto.

The reward pathway, in the most basic sense, begins in the floor of the midbrain at the (clue: VTA), which then projects to the . This structure then projects finally to the cortex.

Explicação

Questão 2 de 9

1

The reward pathway is also known as the

Selecione uma das seguintes:

  • Mesolimbic Pathway

  • Mesocortical Pathway

  • Nigrostriatal Pathway

  • Tuberoinfundibular Pathway

Explicação

Questão 3 de 9

1

The mesolimbic pathway is one of the four ...

Selecione uma das seguintes:

  • Dopaminergic Pathways

  • Adrenergic Pathways

  • Glutamatergic Pathways

Explicação

Questão 4 de 9

1

In terms of the nucleus accumbens, overexpression of which gene transcription factor is thought to be the main influencer of addiction?

Selecione uma das seguintes:

  • ΔFosB

  • ΔJunD

  • cAMP

  • CREB

  • NFκB

Explicação

Questão 5 de 9

1

Patients showing addictive behaviours tend to have a preserved insight; they know they are unwell.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 6 de 9

1

Dopamine release usually has the ability to update info and set new goals in the prefrontal cortex, thus having the ability to avoid compulsive repetition of a behaviour. Addictive drugs provide a potent dopamine signal which disrupts the normal dopamine learning pathway in the prefrontal cortex.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 7 de 9

1

On average, those who start experimenting with drugs earlier in life tend to have a shorter relationship with drugs.

Selecione uma das opções:

  • VERDADEIRO
  • FALSO

Explicação

Questão 8 de 9

1

Which part of the frontal cortex concerns the following:
Emotion and reward in decision making; hyperactivity of this area during addiction behaviour represents craving

Selecione uma das seguintes:

  • Orbitofrontal Cortex

  • ‎Ventrolateral Prefrontal Cortex

  • ‎Dorsolateral Prefrontal Cortex

Explicação

Questão 9 de 9

1

Selecione das listas do Menu para completar o texto.

In ( non-addicted, addicted ) brains, areas such as the Anterior Cingulate Gyrus send inhibitory signals to the orbitofrontal cortex and thus the sensation of craving ( does not, does ) occur.
In ( addicted, non-addicted ) brains, the nucleus accumbens sends inhibitory signals to areas such as the Anterior Cingulate Gyrus so that the inhibitory signals are not sent to the Orbitofrontal cortex and thus the sensation of craving ( does, does not ) occur

Explicação

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