NS 17 - opioid analgesics

Types of Pain (3)

Nociceptive pain pathway

Inflammatory mediators in nociceptive pathway (6)

Endogenous opioids (+precursor) + opioid receptors

Opioid receptor

MoA of miu-opioid receptors

Non-classical opioid receptors/lingands

Pain treatments (4)

Opiates

Opioids

Opioid receptor subtypes

Morphine

Pharmacokinetics of Morphine

SEs of Morphine (8)

Limitations of Morphine (2)

Opioid Agonist Subtypes (3)

Weak agonists (2)

Codeine

Tramadol

Strong agonists (2)

Fentanyl

Methadone

Opioid partial agonist

Buprenorphine

Opioid antagonists

Naloxone