Erin Urbanowicz
Quiz por , criado more than 1 year ago

Quiz sobre NSF Week 7, criado por Erin Urbanowicz em 01-10-2019.

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Erin Urbanowicz
Criado por Erin Urbanowicz aproximadamente 5 anos atrás
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NSF Week 7

Questão 1 de 30

1

Your patient has experienced traumatic events in his past. During which stage of the memory processing of the traumatic event might there be a target for intervention?

Selecione uma das seguintes:

  • consolidation

  • encoding

  • reconsolidation

  • retrieval

Explicação

Questão 2 de 30

1

A 65 year-old right-handed man was brought to the emergency room by his wife one hour after sudden onset of right upper arm/hand weakness and difficulty talking. His wife reported that he seems to understand what she is saying because he is responding appropriately to her questions. However, she states he is only able to produce a few words (e.g."something...wrong...can't talk...doctor"). A physical exam revealed full visual fields, but weakness of the right arm and the right lower face. Which one of the following types of aphasia does the patient demonstrate?

Selecione uma das seguintes:

  • broca's aphasia

  • Anomic Aphasia

  • Global Aphasia

  • Wernicke's Aphasia

Explicação

Questão 3 de 30

1

According to the DSM-5, which of the following is a symptom of Autism Spectrum Disorder?

Selecione uma das seguintes:

  • Difficulty with social interaction

  • Outbursts of anger and disruptive behavior

  • severe anxiety

  • intellectual disability

Explicação

Questão 4 de 30

1

A 19 year old presents to clinic with her mother. She suffered from a traumatic brain injury in a motor vehicle accident when celebrating her 18th birthday. She has had significant problems with school performance and daily functioning. Her mother is concerned about her daughter's cognitive ability since the accident and wants to know if her daughter has an intellectual disability. What additional finding would be required for diagnosis of an intellectual disability?

Selecione uma das seguintes:

  • A score of <80 on IQ testing following the accident

  • Presence of MRI abnormality

  • Rating of a 'severe' impairment on neuropsychological testing in any of the following domains: working memory, attention, or executive skills

  • History of difficulties with cognitive and adaptive skills prior to the accident

Explicação

Questão 5 de 30

1

A 7 year old child presents to your clinic with his foster parents. They are concerned about his school performance and wonder if he may have ADHD. On exam, you note that he is small for his age with a head circumference <5%, has a thin upper lip with flat philtrum, and is very hyperactive (see image). His language skills are on par with those of a 4 year old. Based on this constellation of symptoms, you believe this can be attributed to the most common teratogenic cause of intellectual disability. What prenatal exposure do you suspect?

Selecione uma das seguintes:

  • cigarette smoke

  • alcohol

  • methamphetamines

  • valproic acid

Explicação

Questão 6 de 30

1

Which thalamic nucleus communicates with other thalamic nuclei and also prevents overstimulation of cortex via GABAergic cortical relays?

Selecione uma das seguintes:

  • Pulvinar

  • Reticular

  • Intralaminar

  • Anterior

Explicação

Questão 7 de 30

1

Which of the following functions does the pineal body regulate?

Selecione uma das seguintes:

  • Circadian rhythms through the release of melatonin

  • Food intake through the release of leptin

  • Water intake by measuring blood osmolality

  • "Fight or Flight" response through the release of Corticotropin Releasing Hormone

Explicação

Questão 8 de 30

1

Thalamic pain syndrome (Dejerine-Roussy syndrome) results from a lesion of which thalamic nucleus?

Selecione uma das seguintes:

  • Mediodorsal

  • Pulvinar

  • ventral posterior

  • reticular

Explicação

Questão 9 de 30

1

Which of the following hypothalamic nuclei are associated with the Papez circuit and memory?

Selecione uma das seguintes:

  • paraventricular nuclei

  • mammillary bodies

  • supraoptic nuclei

  • preoptic nuclei

Explicação

Questão 10 de 30

1

Orexin, a neuropeptide responsible for wakefulness, arousal, and increased appetite, is released by which hypothalamic nucleus/nuclei?

Selecione uma das seguintes:

  • Ventromedial nuclei

  • mammillary body

  • arcuate nucleus

  • lateral nuclei

Explicação

Questão 11 de 30

1

On the SLUMS, a patient's memory is tested by determining if a list of 5 words can be registered immediately and recalled again in 5 minutes. What type of memory is being tested with 5 minute recall?

Selecione uma das seguintes:

  • Working

  • Sensory

  • Declarative

  • Implicit

Explicação

Questão 12 de 30

1

A 45 year old man has had a stroke in his dominant hemisphere. On mental status evaluation, you determine that he constructs sentences with articles and prepositions, with average sentence length of 7-8 words. The sentences have normal intonation and he does not make frequent pauses in his speech. He frequently answers 'yes' to open-ended questions. You have difficulty understanding the content of his responses, despite normal articulation. Which area is most likely affected by his stroke?

Selecione uma das seguintes:

  • Parahippocampal gyrus

  • Superior parietal lobe

  • Posterior superior temporal gyrus

  • cingulate gyrus

Explicação

Questão 13 de 30

1

Which nucleus is involved in memory formation, providing cholinergic input to the hippocampus?

Selecione uma das seguintes:

  • Raphne nucleus

  • Locus Ceruleus

  • Nucleus basalis of Meynert

  • Nucleus Accumbens

Explicação

Questão 14 de 30

1

A 33 year old man has 5 days of progressively worsening mental status with fever. He has a first-time seizure in the emergency room. An MRI brain shows hemorrhagic lesions in the bilateral temporal lobes. Based on the most likely diagnosis, what next steps do you take?

Selecione uma das seguintes:

  • Send CSF culture, give ceftriaxone IV

  • Send CSF culture, give oral acyclovir

  • CSF PCR, no available treatments

  • CSF PCR, give IV acyclovir

Explicação

Questão 15 de 30

1

A 19 year old man has new onset of altered mental status, fever, and new-onset seizures. His MRI brain shows temporal lobe cerebritis. A lumbar puncture shows normal glucose and protein, but a mild pleiocytosis (18 white blood cells) with lymphocytic predominance (92% lymphocytes). These findings suggests that he has which of the following?

Selecione uma das seguintes:

  • Enterovirus

  • West Nile Virus

  • Neisseria Meningtidis

  • Bartonella Henselae

Explicação

Questão 16 de 30

1

A general pediatrician screens an 18 month old girl at a well-child visit and finds a lack of joint attention by history and examination. She refers her on for a formal diagnostic evaluation at a development clinic with a multidisciplinary autism spectrum disorders team. On her exam, which of the following suggests an absence of joint attention?

Selecione uma das seguintes:

  • She became overly fixated on one toy and spent the rest of the appointment spinning its wheels

  • She does not follow instructions when you ask her to run down the hallway

  • She will not simultaneously regard a toy to which her mother and doctor are both pointing

  • She repetitively licks the screen of her mother's tablet

Explicação

Questão 17 de 30

1

In the Papez circuit, which brain structure receives input from various cortical areas and is the primary source of input to the hippocampus?

Selecione uma das seguintes:

  • Subiculum

  • Entorhinal cortex

  • Fornix

  • Cingulum

Explicação

Questão 18 de 30

1

Delirium can be distinguished from depression, dementia, and schizophrenia based on the mental status exam. Which of the following symptoms are characteristic of delirium, and not typical of depression, dementia, or schizophrenia?

Selecione uma das seguintes:

  • Delusions and hallucinations

  • Tearfulness and other mood changes

  • acute onset with fluctuating symptoms

  • Impaired short-term memory

Explicação

Questão 19 de 30

1

Iatrogenic causes of delirium often include medications. Which of the following medications is likely to cause and/or worsen delirium in hospital patients?

Selecione uma das seguintes:

  • Haloperidol (antipsych)

  • Lorazepam (benzo)

  • clonidine (alpha-2 agonist)

  • acetaminophen

Explicação

Questão 20 de 30

1

The anatomic distribution of which abnormality in the brain is most closely correlated with the clinical progression of Alzheimer's disease?

Selecione uma das seguintes:

  • Plaques composed of oxidized lipids

  • Neurofibrillary tangles composed of tau

  • Lewy bodies composed of alpha synuclein

  • Prion plaques composed of prion protein

Explicação

Questão 21 de 30

1

What is the name of the extracellular protein aggregate that is a marker of Alzheimer's disease?

Selecione uma das seguintes:

  • Beta Amyloid

  • Neurofibrillary tangle

  • Alpha Synuclein

  • Prion protein

Explicação

Questão 22 de 30

1

REM sleep behavior disorder is a core feature of which dementia?

Selecione uma das seguintes:

  • Alzheimer Disease

  • Frontotemporal dementia

  • Lewy body dementia

  • Vascular Dementia

Explicação

Questão 23 de 30

1

What MRI finding would you most likely observe in a patient with moderate to severe Alzheimer's disease?

Selecione uma das seguintes:

  • Abnormal T2 signal w/in the hippocampus

  • Abnormal T2 signal w/in the brainstem

  • Frontal lobe atrophy

  • Bilateral hippocampal atrophy

Explicação

Questão 24 de 30

1

A 57-year old lawyer presents with a 1-2 year history of increased impulsivity and disinhibition, leading to the recent loss of his job. His wife describes him as having a tendency to become fixated on one idea without being able to let it go (over the same time period). During the exam, he is extremely jovial and intermittently makes inappropriate comments. Lab workup is normal. What type of neurocognitive disorder is most likely?

Selecione uma das seguintes:

  • Alzheimer's Dementia

  • Lewy Body Dementia

  • Mild Cognitive impairment

  • Frontotemporal dementia

Explicação

Questão 25 de 30

1

What is the most common type of Creutzfeldt-Jakob disease (CJD)?

Selecione uma das seguintes:

  • Sporadic

  • Iatrogenic

  • Variant

  • Familial

Explicação

Questão 26 de 30

1

What is the major output tract of the amygdala?

Selecione uma das seguintes:

  • Stria terminalis

  • Fornix

  • Cingulum

  • Medial forebrain bundle

Explicação

Questão 27 de 30

1

An elderly patient dies from aspiration pneumonia, after a prolonged cognitive decline over several years, characterized mostly by memory loss. There was not significant motor dysfunction. Neuropathological examination of the brain and spinal cord is most likely to reveal which of the following?

Selecione uma das seguintes:

  • Alpha-synuclein positive Lewy bodies in the cortex and midbrain

  • Tau-positive inclusions in the anterior horn cells of the spinal cord

  • Amyloid-beta and Tau positive plaques throughout the cortex

  • Amyloid-beta deposits in vessel walls only

Explicação

Questão 28 de 30

1

An adult patient dies after approximately two years of progressive muscle weakness, eventually requiring ventilator support. Early symptoms included hyperreflexia and spasticity. Cognitive function was intact, and no significant cortical atrophy was seen on gross examination. Neuropathological examination of the brain and spinal cord is most likely to reveal which of the following?

Selecione uma das seguintes:

  • Alpha-synuclein positive Lewy bodies in the cortex and midbrain

  • Tau-positive inclusions in the anterior horn cells of the spinal cord

  • Amyloid-beta and Tau positive plaques throughout the cortex

  • Amyloid-beta deposits in vessel walls only

Explicação

Questão 29 de 30

1

Which of the following is required to make a diagnosis of ADHD?

Selecione uma das seguintes:

  • Family history of ADHD

  • Inattention

  • Hyperactivity

  • Age of onset in childhood

Explicação

Questão 30 de 30

1

Which of the following is a common dose dependent side effect of first line medications used to treat ADHD?

Selecione uma das seguintes:

  • Polyuria

  • Elevated blood pressure

  • Blurry vision

  • diarrhea

Explicação