Mer Scott
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PHCY320 (Neurology) Quiz sobre NE1 Intro and CNS revision, criado por Mer Scott em 09-10-2019.

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Mer Scott
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NE1 Intro and CNS revision

Questão 1 de 5

1

Message from brain or spinal cord to the muscles, organs is .
Message from receptors to the brain or spinal cord is .
Interneuron relays between neurons.
Information flows from one neuron to another across a synapse, changing to and back.
• Target cell MORE likely to fire =
• Target cell LESS likely to fire =
= ‘decides’ whether to fire AP
summation: different locations at same time
summation: same place, slightly different times

Arraste e solte para completar o texto.

    efferent
    afferent
    sensory and motor
    action potential
    neurotransmitter
    excitatory
    inhibitory
    Integration
    Spatial
    Temporal

Explicação

Questão 2 de 5

1

Neurotransmitters:
Conventional -
1. Small molecules
• Amino acids:
• Biogenic amines: noradrenaline, serotonin, histamine
• Purines:
2.
3. Neuropeptides: Neuropeptide Y

Non conventional -
1.
2. Gasotransmitters:

Arraste e solte para completar o texto.

    Glutamate, glycine, GABA
    Dopamine, adrenaline,
    ATP, adenosine
    Acetylcholine
    Enkephalin, endorphins, substance P,
    carbon monoxide, nitric oxide
    Endocannabinoids

Explicação

Questão 3 de 5

1

Choose the correct statement.

Selecione uma das seguintes:

  • Glutamate is the main excitatory NT

  • GABA is the main inhibitory NT in the spinal cord

  • Glycine is the main inhibitory NT in the brain

Explicação

Questão 4 de 5

1

Selecione das listas do Menu para completar o texto.

Aspects of neurotransmission (synthesis, storage, release, reuptake) are affected by many drugs. General drug effects:
1. Storage
Facilitates storage (e.g., by acting as a precursor) – ( agonist, antagonist )
Inhibits storage (e.g.by inhibiting synthesis or by blocking storage into vesicles) – ( antagonist, agonist )

2. Release
Increases release – ( agonist, antagonist )
Prevents release – ( antagonist, agonist )

3. Reuptake/breakdown
Facilitates reuptake/breakdown - ( antagonist, agonist )
Inhibits reuptake/breakdown - ( agonist, antagonist )

Explicação

Questão 5 de 5

1

Drugs affecting dopaminergic neurons:
Synthesis - facilitates synthesis of DA by acting as a precursor - agonist
Storage - blocks DA uptake into vesicles – antagonist
Action - prolongs action of DA by blocking degradation (MAO-B inhibitor) - agonist
Release - Amphetamine increases release of DA - agonist
Reuptake - and amphetamine blocks DA reuptake - agonist

Drugs affecting serotonergic(5-HT) neurons:
Synthesis - α-Methyltyrosine inhibits synthesis of 5-HT - antagonist
Release - facilitates the release of 5-HT - agonist
Reuptake - blocks reuptake of 5-HT- agonist

Arraste e solte para completar o texto.

    L-DOPA
    Reserpine
    Selegeline
    Cocaine
    Fluoxetine
    Fenfluramine

Explicação