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Aspects of neurotransmission (synthesis, storage, release, reuptake) are affected by many drugs. General drug effects:
1. Storage
Facilitates storage (e.g., by acting as a precursor) – ( agonist, antagonist )
Inhibits storage (e.g.by inhibiting synthesis or by blocking storage into vesicles) – ( antagonist, agonist )
2. Release
Increases release – ( agonist, antagonist )
Prevents release – ( antagonist, agonist )
3. Reuptake/breakdown
Facilitates reuptake/breakdown - ( antagonist, agonist )
Inhibits reuptake/breakdown - ( agonist, antagonist )