Which trafficking pathway is highlighted in the picture?
Biosynthetic pathway
Endocytic pathway
Secretory pathway
Nuclear export pathway
The depicted trafficking pathway is regulated by cellular signals.
Which experiment is a genetic approach to characterize the components and the molecular mechanism of the endomembrane system?
Cell-free systems
Live-cell imaging
Pulse-chase labelling
Mutant phenotype analysis
Which experiments make use of microsomes to study the endomembrane system?
Subcellular fractionation
Which is the organelle with the largest surface area?
Golgi
Endoplasmic reticulum
Plasma membrane
Nucleus
The signal sequence is a short stretch of ❌ amino acids at the ❌ of a nascent protein that serves as an ❌ signal.
SRP stands for "".
Which of the following is a multi-protein complex with an hour-glass shaped aqueous pore?
NPC
Sec61
SRP
Proteosome
TMD stands for "".
TMD is a short stretch of hydrophobic amino acids which serves as a .
UPR () initiates pathways that lead to either the production of more chaperone protein or a global reduction in protein synthesis to alleviate ER stress.
The process in which misfolded proteins are shuttled out of the ER to the where the oligosaccharide chain is removed and the protein is degraded in the is called ().
During core modification of a glycoprotein, the last remaining glucose is removed by
Glycosidase I
Glycosidase II
Glycosidase III
Calnexin
UGGT is an ER chaperone which recognizes hydrophobic negatively charged hydrophilic( hydrophobic, negatively charged, hydrophilic ) regions of misfolded proteins and tags them for refolding by adding back a glucose fatty acid( glucose, fatty acid ) molecule.
In the endomembrane system, the new membrane can only arise from the existing membrane.
According to current knowledge, which of the following are not components of the endomembrane system?
ER
Lysosome
Endosome
Clathrin-coated vesicle
Mitochondria
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