Clinical Pharmacology Final MCQs- 5th Year PMU

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Drugs half-life is an index for

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Irrational ready-made drug formulations contain

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Drug surveillance is done by

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Adverse drug reactions are the following types

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Drugs contraindicated in the first half of pregnancy are

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For pharmacokinetics in elderly is true

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Reasons for inadequate pharmaceutical availability are

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First phase of clinical trial can be determinated as

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Monitoring of therapeutic plasma concentrations is necessary for

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Pharmacogenetic differences lead to

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Placebo is

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Nocebo effect is

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When patient and doctor are aware of the contents of the formulation, the trial is defined as

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Binding of drugs with plasma proteins is important for

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Adverse drug reactions lead to

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Tobacco smoking

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Categories of ADRs are

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Therapeutic drug monitoring is

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Third phase of clinical trial can be determinated as

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Clearence is an index for

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Adverse drug reactions of methylxanthines are

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Bronchodilators are

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Drugs, used for treatment of chronic heart failure are

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Diuretics, used in chronic liver failure are

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Anti-angina effect of β-blockers is due to

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Adverse drug reactions of dihydropyridine calcium channel antagonists are

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Withdrawal syndrome is observed in treatment with

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Drugs preferred for treatment of hypertensive crisis are

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Which are the main drug groups for treatment of ulcer disease

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Which are non-absorbent antacid drugs

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Point out the correct statement for opioid analgesics

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Which are the therapeutic effects of NSAIDs

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In patients with Gram (-) infections are preferred

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Antimicrobial drugs with renal excretion are

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Surrogates in rational pharmacotherapy are

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Pharmacodynamic changes in elderly are

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Steady-state plasma concentration is

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Bad compliance of the patient may be due to

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Fourth phase of clinical trial can be determinated as

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Drugs clearance is

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β2-mimetics are contraindicated for patients with

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Pethidine is indicated for

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The main mechanism of action of NSAIDs is

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The antibiotics of choice for patients with immune deficits are

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Corticosteroids for systemic application are

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The therapy of cardiac failure should starts

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The most often ADRs of β-blockers are

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For treatment of Prinzmetal angina are used

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Adverse drug reactions of ACE inhibitors are

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Mechanism of antihypertensive drugs are

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Proton pump inhibitors are

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Gastrointestinal mucosa protectors are

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Opioid analgesics are suitable for treatment of

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Which are the indications for prescribing NSAIDs

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Triptans are used for treatment of

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Antimicrobial drugs for hepato-biliary infections are

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Adverse drug reactions of aminoglycosides are

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Indications for using cardiac glycosides in the therapy of congestive heart failure are

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Adverse drug reactions of non-dihyropyridine calcium channel antagonists are

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Anti-angina effects of organic nitrates is done by

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Typical for mixed type of insomnia are the following features

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Which of the following β2-mimetics are used as controllers

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The quality of therapeutic decision (outcomes) can be measured by

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Method of evaluation of cost/benefits ration are

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Diuretics are combined with which of the drugs for treatment of cardiac failure

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β2-mimetics should not be combined with

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Methylxanthines should not be combined with

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Characteristic feature of angiotensin receptor blockers (ARB) are

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Antianginal drugs are

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Antihypertensive drugs are

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Adverse drug reactions of salt losing diuretics are

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Well known drug interactions of proton pump inhibitors are

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Contraindicated during pregnancy or breast feedings drugs are

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In which cases step-wise pain killing approach is used

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Which are the ADRs of NSAIDs the selective COX-2 inhibitors

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Adverse drug reactions of triptans are

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In patients with Gram (+) infections are preferred

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Adverse drug reactions of tetracyclines are

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Adverse drug reactions of quinolones are

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Mechanisms of drug interactions are

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Pharmacokinetic defects are

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Adverse drug reactions of β2-mimetics are

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For treatment of stable angina are preferred

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Adverse drug reactions of nitrates used for acute attacks are

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Which are contraindications for NSAIDs non-selective COX inhibitors

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The benzodiazepines and some barbiturates exert the following ADRs

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Which of the following drugs are used to treat headache

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