Four phases of wound healing
1. ❌
AIM: ❌ ❌
❌ --> ❌ --> ❌
2. ❌
❌ present
❌ remove ❌
3. ❌ & ❌
AIM: ❌
❌ produce ❌ --> ❌ of epi. cells and fibroblasts
Granulation tissue = ❌
4. ❌
Once inflammation finished & new tissue forms - ❌ ❌
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Acute Inflammation
Acute Inflammation
Granulation tissue formation
Granulation tissue formation
replacement of epithelial tissue cells
replacement of epithelial tissue cells
Wound maturation and Remodeling
Wound maturation and Remodeling
To prevent further bleeding
To prevent further bleeding
by blood clotting
by blood clotting
Vessel constriction
Vessel constriction
Platelet plug
Platelet plug
Classical signs of inflammation
Classical signs of inflammation
Neutrophils and Macrophages
Neutrophils and Macrophages
debris from injury
debris from injury
Fill in gap of damaged tissue
Fill in gap of damaged tissue
fibrous connective tissue + capillaries
fibrous connective tissue + capillaries
granulation tissue is replaced by mature
granulation tissue is replaced by mature
connective tissue
connective tissue
growth factors
growth factors
proliferation
proliferation