OCB02-1009-Early tooth development/Late tooth development/Tooth morphogenesis

What are the 5 main stages of tooth development?

What are the two parts of the dental lamina?

Where does dental tissue originate from?

Where do the oral epithelium cells originate from, and what does they become?

Where does the oral mesenchyme cells originate from, and what do they become?

Where are neural crest cells found?

What do defects in the neural crest cells lead to?

Which transcription factors are present in the epithelium? Which are present in the mesenchyme?

What occurs during the initiation stage of tooth development?

What is the primary epithelial band?

What is the dental placode?

What occurs during the bud stage?

During the cap stage, what determines the shape?

What are the cell types in the enamel organ?

Where is the dental papilla located compared to the dental follicle?

What creates the bell shape? What are the two mechanisms in which this happens?

What growth factors does the PEK secrete?

What happens to the PEK eventually? What signals this?

What does the PEK mark?

In multicuspid teeth, when does the secondary enamel knots form? What does the number, timing and layout indicate?

What are the 3 layers of the dental follicle?

What is the cervical loop?
What does the cervical loop become, and what is its function?

When does tooth buds for permanent teeth form? How does this happen?

What is the difference between a successional and an accessional tooth?

What activates tooth generation?

What are the Epithelial Pearls of Serres? What can they lead to?

When does hard tissue (ameloblasts/odontoblasts) start forming at the tip of cusps?

Where are ameloblasts first located? How do they move? What do they lay down?

Where are odontoblasts first located? How do they move? What do they lay down?

Do ameloblasts or odontoblasts differentiate first? What do they secrete?

Does dentin or enamel form first?

How is tooth type determined?

Where is the homeobox code located?

What limits the growth of teeth?

What is the EDA Signalling pathway and what does it lead to?

What are some EDA defects?

What is hypohidrotic ectodermal dysplasia?

What occurs with overexpression of EDAR?