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Oncology Final MCQs- 5th Year PMU Topics- Epidemiology, Carcinogenesis, CNS Tumors, Malignant head and neck Tumors, Malignant lung diseases, Malignant diseases of the mammary gland

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Oncology Final MCQs 1- 5th Year PMU

Questão 1 de 100

1

Preencha os espaços em branco para completar o texto.

EGF-(R) = (Receptor)
ER =
HER =
HPV =
PR =
VEGF (R) = (Receptor)
TKI =
ALK =
CRC =
MCA =

Explicação

Questão 2 de 100

1

According to WHO data by 2030, malignancies will be the leading cause of mortality. What place do they occupy now?

Selecione uma das seguintes:

  • third

  • fourth

  • second

  • first

Explicação

Questão 3 de 100

1

Which are the most often occurring tumors in children up to 10 years of age?

Selecione uma das seguintes:

  • neuroblastoma, leukemias, gastrointestinal tumors

  • acute leukemias, brain tumors, Wilms tumor

  • retinoblastoma, nephroblastoma, gastrointestinal tumors

  • lymphomas, leukemias, brain tumors

Explicação

Questão 4 de 100

1

What are the most common neoplasias in the 2nd and 3rd decades of life?

Selecione uma das seguintes:

  • soft tissue tumors, testicular carcinoma

  • mesenchymal tumors, breast cancer

  • gastrointestinal tumors, osteosarcoma

  • lung cancer, head and neck tumors

Explicação

Questão 5 de 100

1

What are the most common neoplasias in the 3rd and 4th decades of life?

Selecione uma das seguintes:

  • female genital tract tumors, male genital tract tumors

  • breast cancer, uterine cancer, CRC

  • lung cancer, breast cancer, CNS tumors

  • head and neck tumors, sarcomas

Explicação

Questão 6 de 100

1

What are the most common neoplasias after the 5th decade of life?

Selecione uma das seguintes:

  • Lung carcinoma, prostate gland carcinoma

  • Tumors of GIT, bladder carcinoma

  • CRC, prostate and lung carcinoma

  • Head and neck tumors, lung cancer

Explicação

Questão 7 de 100

1

There are differences In cancer morbidity and mortality between males and females. What is the gender predominance of CRC and stomach cancer?

Selecione uma das seguintes:

  • Men

  • Women

  • There is no gender predominance

  • Age-based sex division

Explicação

Questão 8 de 100

1

Depending on geographic latitudes there is differential endemic Spread of neoplasms. Gastric carcinoma occurs predominantly in:

Selecione uma das seguintes:

  • USA, Europe, Japan

  • Asia, Europe

  • Latin America, Eastern Europe, Japan

  • Southeast Asia and Africa

Explicação

Questão 9 de 100

1

CRC occurs with the highest frequency in:

Selecione uma das seguintes:

  • Europe

  • Asia

  • The USA

  • Australia and New Zealand

Explicação

Questão 10 de 100

1

Mammary carcinoma is rare in:

Selecione uma das seguintes:

  • The United States, Asia

  • Europe, Latin America

  • Africa, Asia

  • Australia and New Zealand

Explicação

Questão 11 de 100

1

The Epstein-Barr virus is associated with infectious mononucleosis nasopharyngeal carcinoma, and Burkitt's lymphoma. The latter has marked endemic spread:

Selecione uma das seguintes:

  • The Scandinavian countries, Mongolia

  • Malaysia, Uganda, New Guinea

  • Japan, the Philippines

  • Australia and New Zealand

Explicação

Questão 12 de 100

1

What is screening?

Selecione uma das seguintes:

  • testing a group of people for the detection of early-stage cancers

  • examining a group of people when certain symptoms and complaints are present

  • detection of unplanned disease by tests and procedures that can be applied quickly

  • evidence of disease’s initial symptoms

Explicação

Questão 13 de 100

1

What types of cancer screenings are available?

Selecione uma das seguintes:

  • Lung carcinoma, colon carcinoma, breast cancer

  • CRC, prostate, stomach

  • Breast cancer, prostate, cervical carcinoma

  • CRC, breast cancer, lung carcinoma

Explicação

Questão 14 de 100

1

Which of the following cancers affect predominantly men

Selecione uma das seguintes:

  • lung, prostate, colorectal carcinoma

  • melanoma, pancreas, lung

  • colon, prostate, melanoma

  • lung, pancreas, brain

Explicação

Questão 15 de 100

1

Which tumors in women confer the lowest five-year survival rate?

Selecione uma das seguintes:

  • breast

  • ovary

  • corpus uteri

  • lung

Explicação

Questão 16 de 100

1

Areas with the highest oncological morbidity at present are

Selecione uma das seguintes:

  • Americas

  • Europe

  • Africa

  • Europe and Americas

Explicação

Questão 17 de 100

1

Which tumors in males confer the lowest five-year survival rate?

Selecione uma das seguintes:

  • testicular carcinoma

  • lung cancer

  • prostate cancer

  • colon cancer

Explicação

Questão 18 de 100

1

The most common Malignant tumor in Women is

Selecione uma das seguintes:

  • Mammary Carcinoma

  • Cervical Carcinoma

  • Skin carcinoma

  • Ovarian Carcinoma

Explicação

Questão 19 de 100

1

What is the most accurate definition of carcinogenesis?

Selecione uma das seguintes:

  • The occurrence of mutations in more than one locus leading to the appearance of a transformed cell

  • Multistage and prolonged process leading to transformed cells with subsequent clonal selection and expansion

  • Multistage process of transformation and development of neoplastic clone

  • There is no correct answer

Explicação

Questão 20 de 100

1

Tumorigenesis occurs in three stages

Selecione uma das seguintes:

  • Proliferation, promotion, metastasis

  • Initiation, promotion, proliferation

  • Proliferation, promotion, progression

  • All answers are correct

Explicação

Questão 21 de 100

1

Neoangiogenesis

Selecione uma das seguintes:

  • the ability of cancer cells to metastasize via the blood and to form new vessels

  • uncontrolled growth of tissue that can deliver distant metastasize via the blood and the lymphatics

  • uncontrolled development of tissue with the ability to grow and metastasize by forming new vessels

  • there is no correct answer

Explicação

Questão 22 de 100

1

Key features of the tumor cell are

Selecione uma das seguintes:

  • ability to proliferate, metastasize, form new vessels and the possibility of apoptosis, invasion

  • loss of apoptosis, endless division, invasion and metastasis

  • generates signals for growth and development, ability to form new vessels and metastasize via the blood

  • all answers are correct

Explicação

Questão 23 de 100

1

What is the definition of benign tumors?

Selecione uma das seguintes:

  • varying degrees of cellular and structural differentiation, do not metastasize

  • highly differentiated tumors whose cells resemble those from which they originated

  • a high degree of cell differentiation, the presence of functional activity and metastatic ability

  • answers a+c

Explicação

Questão 24 de 100

1

Which statement about malignant tumors is wrong?

Selecione uma das seguintes:

  • varying degrees of cell differentiation and structural organization

  • cells are organized in monolayers with signs of anaplasia

  • have an infiltrative growth

  • there is no correct answer

Explicação

Questão 25 de 100

1

What is relapse?

Selecione uma das seguintes:

  • a newly emerging tumor

  • the reappearance of a tumor following its surgical removal

  • the appearance of a tumor at the same site as the one removed

  • the appearance of regional lymph nodes

Explicação

Questão 26 de 100

1

Malignant tumors have infiltrative growth, cellular atypism, are encapsulated capsule and have the ability to give regional and distant metastases.
This statement is

Selecione uma das seguintes:

  • true

  • untrue

  • incomplete

  • ambiguous

Explicação

Questão 27 de 100

1

Mesenchymal tumors metastasize

Selecione uma das seguintes:

  • Via lymphatics

  • Via blood

  • Canalicularly

  • Intracavitary

Explicação

Questão 28 de 100

1

The tumors of __________ metastasize in Intravascular fashion

Selecione uma das seguintes:

  • lung, stomach, intestine

  • ovaries, uterus, bladder

  • head and neck, lung and prostate

  • there is no correct answer

Explicação

Questão 29 de 100

1

Which of the following statements are characteristic of the cancer cell biology

Selecione uma das seguintes:

  • cellular "immortality"

  • angiogenic ability

  • altogether

  • ability to invade and metastasize

Explicação

Questão 30 de 100

1

Indicate which factors are associated with tumor progression

Selecione uma das seguintes:

  • IL-1, IL-6, TNF-α

  • EGF / R, VEGF / R, HER-2, PDGF

  • OPG, RANK, RANKL

  • a+b

Explicação

Questão 31 de 100

1

Paraneoplastic syndrome is due to

Selecione uma das seguintes:

  • tumor progression

  • ectopic secretion of hormone-like peptides and immune response to the tumor

  • metastasis

  • the intoxication of the organism

Explicação

Questão 32 de 100

1

Which tumors are hormone-dependent in their development

Selecione uma das seguintes:

  • breast carcinoma

  • colon carcinoma

  • endometrial carcinoma

  • all listed

Explicação

Questão 33 de 100

1

Genetic changes leading to carcinogenesis are

Selecione uma das seguintes:

  • Spontaneous mutations in cell cycle regulating genes

  • Mutations in genes regulating the replication and repair of DNA

  • Multiple mutations

  • All answers are correct

Explicação

Questão 34 de 100

1

Characteristics of neoplastic cells are

Selecione uma das seguintes:

  • loss of apoptosis

  • high proliferative potential

  • tendency for invasion

  • each indicated

Explicação

Questão 35 de 100

1

The most common primary brain tumors are

Selecione uma das seguintes:

  • anaplastic astrocytomas

  • glioblastomas

  • oligodendrogliomas

  • there is no true answer

Explicação

Questão 36 de 100

1

The mean survival rate for malignant CNS tumors is

Selecione uma das seguintes:

  • 5-10 months

  • 15-18 months

  • 2 years

  • One year

Explicação

Questão 37 de 100

1

A radical method for the treatment of solitary («3 cm) CNS tumors is

Selecione uma das seguintes:

  • radiotherapy of the brain

  • radiosurgery

  • operative treatment

  • chemotherapy

Explicação

Questão 38 de 100

1

Radiation is an important part of the complex treatment.
The total dose of craniotherapy is

Selecione uma das seguintes:

  • 40 Gy

  • 60 Gy

  • 80 Gy

  • There is no true answer

Explicação

Questão 39 de 100

1

Chemotherapy incorporates

Selecione uma das seguintes:

  • Cisplatin

  • Gemcitabine

  • Temozolamide

  • There is no true answer

Explicação

Questão 40 de 100

1

Medulloblastoma is predominantly located in the rear cranial well and occurs most commonly in

Selecione uma das seguintes:

  • The 3rd and 4th decades of life

  • Childhood

  • 2nd and 3rd decade of life

  • Newborns

Explicação

Questão 41 de 100

1

The main methods of diagnosis and follow-up of treatment effect in CNS tumors are

Selecione uma das seguintes:

  • CT and MRI

  • MRI and PET scan

  • CT and PET scan

  • All answers are correct

Explicação

Questão 42 de 100

1

Symptomatic therapy in CNS tumors includes

Selecione uma das seguintes:

  • dexamethasone, tranquilizers, diuretics

  • anxiolytics, diuretics

  • anticonvulsants, diuretics, dexamethasone

  • all answers are correct

Explicação

Questão 43 de 100

1

Brain metastases are yielded most commonly by

Selecione uma das seguintes:

  • Prostate and lung carcinoma

  • Thyroid and gastric carcinoma

  • Carcinoma of the mammary gland and lung carcinoma

  • Kidney and GIT carcinoma

Explicação

Questão 44 de 100

1

Which treatment method will be preferred for solitary brain metastasis

Selecione uma das seguintes:

  • Brachytherapy

  • Percutaneous external irradiation

  • Operational extirpation

  • Radiosurgery

Explicação

Questão 45 de 100

1

Temozolamide used to treat brain tumors belongs to which group of cytostatics based on its mechanism of action

Selecione uma das seguintes:

  • anthracycline

  • antimetabolite

  • an alkylating agent

  • atyrosine kinase inhibitor

Explicação

Questão 46 de 100

1

Methods for the treatment of multiple brain metastases are

Selecione uma das seguintes:

  • surgery

  • radiotherapy

  • chemotherapy

  • b+c

Explicação

Questão 47 de 100

1

Preencha os espaços em branco para completar o texto.

List the symptoms of increased intracranial pressure
behaviour

Feeling less alert than usual

Lack of energy or sleepiness

Weakness or problems with moving or talking

Explicação

Questão 48 de 100

1

Risk factors for head and neck tumors are

Selecione uma das seguintes:

  • chronic etilism, 3rd and 4th decade of life, male Sex, tobacco chewing

  • smoking, systemic use of alcohol and mutation in p53 gene

  • female sex, smoking, alcohol abuse

  • all answers are correct

Explicação

Questão 49 de 100

1

The most common head and neck tumors metastasize

Selecione uma das seguintes:

  • Via lymphatics

  • Via blood

  • Ref. a+b

  • Neighborhood invasion/ local invasion

Explicação

Questão 50 de 100

1

Head and neck tumors occur with the highest frequency at which anatomic sites

Selecione uma das seguintes:

  • The oral cavity

  • Oropharynx

  • Larynx

  • Sinus

Explicação

Questão 51 de 100

1

The characteristic clinical picture includes

Selecione uma das seguintes:

  • pain, fever, soore, difficulty swallowing

  • ulcer. dysphagia, otalgia

  • dysphagia, dyspnoea, swelling in the neck, soor

  • all answers are correct

Explicação

Questão 52 de 100

1

The most common histology of head and neck tumors is

Selecione uma das seguintes:

  • adenocarcinomas

  • epidermoid carcinomas

  • squamous cell carcinomas

  • there is no true answer

Explicação

Questão 53 de 100

1

A leading treatment approach for head and neck tumors is

Selecione uma das seguintes:

  • radiotherapy

  • chemotherapy

  • chemoradiotherapy

  • all answers are correct

Explicação

Questão 54 de 100

1

The most common early radiation reactions are

Selecione uma das seguintes:

  • dysphagia and oropharyngeal mucositis

  • reduced hearing and odinophagia

  • larynx edema

  • a+c

Explicação

Questão 55 de 100

1

Late radiation complications are

Selecione uma das seguintes:

  • trismus, reduced hearing

  • oropharyngeal mucositis and dysphagia

  • radiographic fibrosis

  • a+c

Explicação

Questão 56 de 100

1

The gold standard for nasopharyngeal carcinoma is

Selecione uma das seguintes:

  • surgery, radiation, chemotherapy

  • operative intervention and subsequent radiotherapy

  • combined chemoradiotherapy

  • all the options listed

Explicação

Questão 57 de 100

1

Targeted therapy for head and neck tumors is performed with

Selecione uma das seguintes:

  • Bevacizumab

  • Cetuximab

  • Panitumumab

  • Nivolumab

Explicação

Questão 58 de 100

1

HPV is related to the etiology of

Selecione uma das seguintes:

  • cervical carcinoma

  • anogenital carcinoma

  • head and neck carcinoma

  • all listed

Explicação

Questão 59 de 100

1

Head and neck tumors include neoplasia originating from anatomical locations

Selecione uma das seguintes:

  • salivary glands, larynx, pharynx, oral cavity, nasal cavity, maxillary, frontal, ethmoidal, sphenoidal sinus

  • larynx, pharynx, oral and nasal cavities, parotid gland

  • parotid gland, larynx, pharynx, oral cavity, nasal cavity, paranasal sinuses

  • parotid gland, larynx, pharynx, oral cavity, nasal cavity, maxillary, frontal, ethmoidal sinus

Explicação

Questão 60 de 100

1

Tumors of head and neck are characterized by

Selecione uma das seguintes:

  • increased frequency in Central Asia

  • mainly affect female subjects

  • most common in the western world

  • a+b

Explicação

Questão 61 de 100

1

Preencha os espaços em branco para completar o texto.

Complete the term against the relevant definition of premalignant lesions that are associated with the development of squamous cell carcinoma:
- hyperkeratosis + underlying epithelial hyperplasia
- superficial erythema spots near to normal mucosa due to epithelial dysplasia

Explicação

Questão 62 de 100

1

The therapeutic approach to advanced disease includes

Selecione uma das seguintes:

  • protocols with combined modality (radiochemotherapy)

  • radical surgery

  • administration of platinum-based chemotherapy protocol

  • the combined use of surgery radiotherapy

Explicação

Questão 63 de 100

1

The four major histological types of lung carcinoma are

Selecione uma das seguintes:

  • large cell, squamous, papillary, small cell

  • small cell, squamous cell, adenocarcinoma, large cell

  • spinocellular, acinar, small cell, large cell

  • there is no correct answer

Explicação

Questão 64 de 100

1

Which histological type has the worst prognosis?

Selecione uma das seguintes:

  • spinocellular

  • acinar adenocarcinoma

  • small cell

  • there is no true answer

Explicação

Questão 65 de 100

1

What are the principal biomarkers for NSCLC?

Selecione uma das seguintes:

  • EGFR, HER-2

  • K-RAS, HER-2

  • ALK, PDL-1

  • EGFR, ALK, PDL-1

Explicação

Questão 66 de 100

1

The standard for ChTh in radically operated patients with NSCLC is

Selecione uma das seguintes:

  • APCT containing taxane

  • APCT containing cisplatin

  • APCT containing vinorelbine

  • APCT containing anthracyclines

Explicação

Questão 67 de 100

1

Target therapies for NSCLC include

Selecione uma das seguintes:

  • Bevacizumab, Panitumumab, Nivolumab

  • Erlotinib, Gefitinib, Crizotinid

  • Pertuzumab, Cetuximab, Pembrolizumab

  • There is no true answer

Explicação

Questão 68 de 100

1

Malignant Mesothelioma is characterized by (one wrong answer)

Selecione uma das seguintes:

  • The main method of treatment is chemotherapy

  • Origin from the pleura, pericardium, peritoneum, testicular envelopes.

  • A causal relationship with exposure to asbestos

  • There are a large percentage of patients with five years of survival

Explicação

Questão 69 de 100

1

Which of the following statements about lung carcinoma is NOT correct

Selecione uma das seguintes:

  • more prominent for developed countries

  • the main cause of cancer morbidity and mortality in women

  • there are 2 major histological types - small cell and non-small cell

  • has a high-sensitivity tumor marker for diagnosis

Explicação

Questão 70 de 100

1

Which of the following statements for small cell lung cancer (SCLC) compared to non-small cell lung cancer (NSCLC) is true

Selecione uma das seguintes:

  • SCLC is more radiosensitive

  • SCLC is less chemosensitive

  • SCLC is more likely to have a peripheral localization in the lung

  • Tendency towards early and rapid metastasis

Explicação

Questão 71 de 100

1

73 years old man has an increasing pain in the lumbar segment of the spine, more pronounced at bedtime. From the history - a long-standing hypertonic; sometimes smokes 1-2 cigarettes a week. Physical status is normal. Laboratory studies have found elevated serum alkaline phosphatase levels. From radiograph of the lumbar segment - a lytic bone lesion of the third lumbar vertebra.
Which of the following cancers is the most likely diagnosis:

Selecione uma das seguintes:

  • carcinoma of the stomach

  • non-small cell lung carcinoma

  • sarcoidosis

  • mesothelioma

Explicação

Questão 72 de 100

1

Immunotherapy in lung carcinoma is performed with

Selecione uma das seguintes:

  • BCG vaccine

  • Immunomodulators

  • Nivolumab, Pembrolizumab

  • There is no true answer

Explicação

Questão 73 de 100

1

Pulmonary carcinoma metastasizes most often in

Selecione uma das seguintes:

  • liver

  • pleura and mediastinal lymph nodes

  • brain

  • bones

Explicação

Questão 74 de 100

1

The recommended behavior of a General Practitioner in a patient with a blood clot is

Selecione uma das seguintes:

  • Follow-up for one month

  • X-ray and consultation with a pneumologist no later than two weeks

  • CT scan

  • X-ray and surgery referral

Explicação

Questão 75 de 100

1

What is the significance of EGFR expression Studies, KRAS mutation and ALK in non-small cell lung carcinoma

Selecione uma das seguintes:

  • They are prognostic markers for survival

  • Reference markers for surgery

  • EGFR-TKI response markers

  • Possibility for personalized treatment

Explicação

Questão 76 de 100

1

Which factors are not carcinogens for lung cancer

Selecione uma das seguintes:

  • Smoking

  • Radiation

  • A diet rich in fat

  • Avitaminoses

Explicação

Questão 77 de 100

1

Hypertrophic pulmonary osteoarthropathy is

Selecione uma das seguintes:

  • Symptom of Peak Lung Cancer Symptom

  • Complication of radiotherapy

  • Paraneoplastic syndrome in lung carcinoma

  • Paraneoplastic syndrome in ovarian cancer

Explicação

Questão 78 de 100

1

Contemporary molecular genetic tests on lung cancer biopsy specimen include

Selecione uma das seguintes:

  • EGFR mutation

  • PDF

  • ALK

  • All answers are correct

Explicação

Questão 79 de 100

1

Peripheral lung lesions suspect for carcinoma are indicated for further diagnostic testing with

Selecione uma das seguintes:

  • Surgical resection

  • Transthoracal needle biopsy

  • Bronchoscopy

  • Mediastinoscopy

Explicação

Questão 80 de 100

1

For pleural effusion suspicious of lung carcinoma indicated is

Selecione uma das seguintes:

  • X-ray and consultation with a pulmonologist

  • VATS (video-assisted thoracoscopy) with a biopsy

  • Magnetic resonance tomography

  • Positron emission tomography

Explicação

Questão 81 de 100

1

Palliative therapy in lung cancer is

Selecione uma das seguintes:

  • associated with a high risk of fatal toxicity

  • associated with increased life expectancy at reduced quality of life

  • followed by a 1 year life expectancy at improved quality of life

  • does not change life expectancy

Explicação

Questão 82 de 100

1

Which statement is true for Luminous type A?

Selecione uma das seguintes:

  • ER, PR- positive, HER2- negative, low Ki 67

  • ER PR- positive, HER2-positive, low Ki 67

  • ER, PR- positive, HER2- negative, high Ki 67

  • There is no correct answer

Explicação

Questão 83 de 100

1

Which statement is wrong for Luminous Type B?

Selecione uma das seguintes:

  • ER, PR- positive, HER2- negative, high Ki 67

  • ER, PR- positive, HER2- overexpression, regardless of Ki 67

  • ER, PR- positive, HER2- positive, low Ki 67

  • No wrong answer

Explicação

Questão 84 de 100

1

In non-luminous type we observe?

Selecione uma das seguintes:

  • ER, PR- negative, HER2- overexpression

  • ER, PR- positive, HER2-positive, Ki 67 low

  • ER, PR- positive, HER2- negative

  • There is no correct answer

Explicação

Questão 85 de 100

1

Genetic mutations in breast carcinoma are

Selecione uma das seguintes:

  • BRCA 1, BRCA 2

  • BRCA1, BRCA2, p53

  • ALK, PDL 1

  • All listed

Explicação

Questão 86 de 100

1

Standard treatment for luminal type A breast carcinoma includes

Selecione uma das seguintes:

  • chemotherapy

  • hormone therapy

  • hormone therapy +/- chemotherapy at positive lymph nodes

  • there is no true answer

Explicação

Questão 87 de 100

1

Standard treatment for luminal type B HER 2 negative breast carcinoma includes

Selecione uma das seguintes:

  • chemotherapy

  • hormone therapy

  • hormone therapy +/- chemotherapy

  • all answers are correct

Explicação

Questão 88 de 100

1

Standard treatment for luminal type B HER 2-positive breast carcinoma includes

Selecione uma das seguintes:

  • chemotherapy, anti-HER 2 therapy

  • chemotherapy, hormone therapy, anti- HER 2 therapy

  • hormone therapy, chemotherapy

  • there is no true answer

Explicação

Questão 89 de 100

1

Treatment in triple negative breast carcinoma includes

Selecione uma das seguintes:

  • chemotherapy

  • hormone therapy

  • chemotherapy + hormone therapy

  • chemotherapy, hormone therapy, anti- HER2

Explicação

Questão 90 de 100

1

Specify the standard treatment algorithm for breast cancer T2N1M0 without hormonal expression

Selecione uma das seguintes:

  • PCT, surgery, radiotherapy

  • Surgery, PCT, radiotherapy

  • Radiotherapy, surgery, PCT

  • The three answers are correct

Explicação

Questão 91 de 100

1

Specify the main tumor marker for diagnosis of breast cancer

Selecione uma das seguintes:

  • CEA

  • CA 15-3

  • HGT

  • CA 19-9

Explicação

Questão 92 de 100

1

The biological characteristic of the "triple-negative" breast cancer requires (choose one wrong answer)?

Selecione uma das seguintes:

  • maximum severity of therapeutic behavior

  • hormonal therapy

  • strict monitoring due to the risk of early relapse and metastasis

  • affects younger women

Explicação

Questão 93 de 100

1

Indicate which target drugs are used in HER positive breast cancer

Selecione uma das seguintes:

  • Avastin, Panitumumab, Cetuximab

  • Herceptin, Lapatinib, Perjeta

  • Tarceva, Iressa, Avastin

  • Herceptin, Nivolumab, Crisotinib

Explicação

Questão 94 de 100

1

A method of early detection (screening) of breast cancer is

Selecione uma das seguintes:

  • Echography

  • Mammography in 2 projections

  • CT

  • MRI

Explicação

Questão 95 de 100

1

The default markers for breast cancer are

Selecione uma das seguintes:

  • The total CEA and CA 15-3

  • HER, estrogen and progesterone receptors, Ki 67

  • Total CEA and CA 125

  • Serum alkaline phosphatase and LDH

Explicação

Questão 96 de 100

1

In which % of cases the breast cancer has a genetic predisposition

Selecione uma das seguintes:

  • 5%

  • 10%

  • 25%

  • 40%

Explicação

Questão 97 de 100

1

Triple-negative breast cancer belong to which of the listed histological groups?

Selecione uma das seguintes:

  • Luminal A

  • Luminal B

  • Basal-like

  • "Normal" -like

Explicação

Questão 98 de 100

1

A recommended age group to start screening for early detection of breast carcinoma is

Selecione uma das seguintes:

  • women over 60 years of age

  • women over 50 years of age

  • women aged 50-69

  • family-related women, regardless of age

Explicação

Questão 99 de 100

1

All of these factors are associated with a decreased risk of developing breast cancer except for

Selecione uma das seguintes:

  • Negative history of breastfeeding

  • First pregnancy before 18 years of age

  • Men after 15 years of age

  • Natural menopause before 42 years of age

Explicação

Questão 100 de 100

1

Which of the following features is associated with an unfavorable prognosis for breast carcinoma

Selecione uma das seguintes:

  • ER+

  • Low proportion of S-phase cells

  • Overexpression of erbB2 (HER-2)

  • PR+

Explicação