Pharmacology XVI

Administration of digitalis glycosides

Each of the following statements about sodium bisulfite is true when used in local anesthetic solutions EXCEPT one. Which one is this EXCEPTION?

The vasoconstrictor that is NOT recommended for hemostasis due to its predominant effect on the venous rather than the arterial circulation is?

Which of the following is an anticholinesterase that is used in reversing the CNS effects caused due to overdosage of drugs such as atropine, phenothiazines and tricyclic antidepressants?

If applied topically, local anesthetics are absorbed almost as rapid as intravenous administration on

The neuroleptic agent that has high potential for extra pyramidal effects but minimal weight gain when administered is

Death by asphyxiation can immediately result if asthmatics are inadvertently administered with

Each of the following H1 histamine receptor blocking agents are indicated for preventing motion sickness symptoms EXCEPT one. Which one is this EXCEPTION?

A 40 yr old female patient complains of difficulty sleeping and frequent awakenings. After she was put on Drug A for 3 months she started complaining of early morning insomnia, daytime anxiety along with amnesia and confusion. Then her physician withdraws drug A and puts her on Drug B. Within a few days of Drug A’s withdrawal she develops rebound insomnia. The drugs A and B prescribed in her case are respectively:

The NSAID which is an inactive prodrug used in the treatment of rheumatoid arthritis, ankylosing spondylytis, osteoarthritis is

The life-saving drug for methicillin resistant staphylococcal epidermidis (MRSE) is

Each of the following statements are true about neuromuscular blocking agents EXCEPT one. Which one is this EXCEPTION?

On a prescription, directions to the patient are always written at the

The anticancer drug that alkylates the DNA and eventually kills the tumor cells is

The anticoagulant of choice for pregnant women with prosthetic heart valves is

The salicylate that does not cross both the blood-brain barrier and placenta is

Each of the following statements is true about Barbiturates EXCEPT one. Which one is this EXCEPTION?

A 38 yr old male patient undergoing Anti HIV therapy the last 3 years started developing a buffalo hump at the base of the neck, breast enlargement and loss of fat from extremities. The drug used here is?

Each of the following drugs are strictly avoided when prescribing for renal impaired patients EXCEPT one. Which one is this EXCEPTION?

At high doses, the drug metabolism is

Significant first-pass metabolism of morphine occurs in the liver; therefore the intramuscular, subcutaneous or IV injections produce the most reliable responses.

The triptan group drug that is used in treating acute attacks of migraine due to its fast onset of action is

Naloxone readily reverses respiratory depression with only minimal reversal of analgesia; BECAUSE it has a ten-fold higher affinity for kappa receptors than for mu.

The Drug that is used in the emergency management of serious ventricular arrhythmia is

Each of the following statements is true about postmenopausal estrogen replacement therapy EXCEPT one. Which one is this EXCEPTION?

A 60 yr old male African-American patient gives a history of hypertension. He has been taking anti-hypertensive pills the last 20 years and his hospital records reveal creatine clearance levels are never below 50 ml/min. He does not report first-dose syncope, postural hypotension, decreased libido, dry cough but does report occasional hypokalemia and hyperuricemia. The anti-hypertensive drug he has been taking is?

The immunosuppressant drug that selectively inhibits cytokine production and function preventing graft rejection is

A 25 year old male patient complains of toothache and was diagnosed to be suffering from dentoalveolar abscess. His medical records show him to be asthmatic and under daily theophylline therapy. He is allergic to penicillin. Knowing his medical history and current dental infection the antibiotic/antimicrobial agent that should not be prescribed to avoid theophylline toxicity is

Epilepsy that does not respond to phenytoin and may worsen if it is administered is

While treating subcutaneous and systemic mycotic infections, Amphotericin B is contraindicated to combine with

For a drug to be readily absorbed it must

Each of the following signs and symptoms are related to the direct depressant action of the local anesthetic on the central nervous system EXCEPT one. Which one is this EXCEPTION?

A 50 yr old male patient gives a history of Gout. What can be safely prescribed in his case is?