CD4 T cells: The Master Controllers of the Immune System

Where do T cells develop?

What are the two types of T cells?

What are the subcategories of conventional T cells?

What are the subcategories on unconventional T cells?

What is the importance of CD4+ T cells in HIV?

How do T cells recognise antigens?

What distinguishes CD4 T cells from other cells?

Describe the autocrine growth pathway

What do activated CD4+ Th cells do?di

What do Th1 cells produce and which immune response do they control?

What do Th2 cells produce and which immune response do they
(control?

Out of cell-mediated and humoral immunity which one deals with intracellular and which deals with extracellular pathogens?

What do Th1 cells do?

Why don't you make activated macrophages from the start?

Some bacteria are hard to kill such as TB. What happens then?

What does IL-4 induce in B cells?

Explain the concept of 'T-cell help'

How do T cells know to become Th1 or Th2 cells?

In what situation will Th0 turn to Th2?

In what situation does Th0 turn into Th1?

Explain the two manifestations of leprosy?

Explain the two manifestations of Leishmaniasis

What are the two manifestations of Tuberculosis?

Problem with Th2 response in the west

Give an example of a classical IgE-mediated allergy
(Type-I hypersensitivity)

Th0 differentiates into many different transcription factors, state what they are and which cytokines stimulate the differentiate of Th0 to them

What do Th17 and iT-Reg cells make?

Th17 and iT-Reg cells defend against?...

What do a fraction of the activated T and B cells become?

Define the term immunological memory