Where takes place the biosynthesis of fatty acids?
In the mitochondrial matrix
In the mitochondrial membrane
In the cytosol
In the reticulum endoplasmatic
Any of these
Which of the next statements is not true?
AcetylCoA is produced in mitochondria and can not get out by itself
AcetylCoA reacts with oxaloacetate forming citrate
In the cytosol, citrate is going to be transformed into AcetylCoA and oxaloacetate with an enzyme called citrate lyase
Oxaloacetate need to go back to mitochondria and then can participate in lipolysis
The tissues where the biosynthesis of Fatty acids takes place are liver, adipose tissue and mammary gland
Which of these enzymes is regulated during the biosynthesis of fatty acids?
Citrate lyase
AcetylCoA carboxylase
Fatty acid synthase
Acyl protein carrierase
ACP transferase
Which of these is not true?
AcetylCoA carboxylase will be active as a polymer
Acetyl carboxylase will form a polymer in presence of citrate
Acetyl carboxylase will be inactive in presence of Palmitic acid
AcetylCoA carboxylase is active when it is phosphorylated
In a fed state, acetyl CoA will be active and we will produce MalonylCoA
Fatty acid synthase can complete biosynthesis of fatty acids by itself
Which of these statements is not true?
Acyl carrier protein has two different SH groups
One molecule of AcetylCoA will bind to the enzyme fatty acid synthase
One molecule of MalonylCoA will bind to the Acyl carrier protein
During the biosynthesis de novo, when a condensation is produce we obtain one molecule of CO2 and a fatty acid with a double bond between α-Carbon and ß-Carbon
During the biosynthesis de novo, a translocation of the fatty acid from ACP to the FAD is produced and the process repeats again
In which step of biosynthesis de novo a molecule of NADPH is required?
In the condensation
In the dehydration
In the reduction
In the elongation
When will finish the biosynthesis of one fatty acid?
When we obtain a fatty acid with 18C atoms (Palmitic acid)
When we obtain a fatty acid with 16C atoms (Palmitic acid)
When we obtain linoleate
When we obtain α-linoleate
When a double bound in a position higher than 9 is produced
For humans is impossible to introduce a double bond in a fatty acid in a position lower than Carbon nº9
Which of these statements about the synthesis of phosphoglycerides is true?
If the phosphoglyceride does not have Nitrogen, phosphatidic acid is going to react with CTP obtaining CDP-DAG
If the phosphoglyceride does not have Nitrogen, phosphatidic acid will be transformed to diacylglycerol
If the phosphoglyceride does not have Nitrogen, phosphatidic acid is going to react with CTP obtaining diacylglycerol
If the phosphoglyceride does not have Nitrogen, phosphatidic acid will be transformed to diacylglycerol and then is going to react with CTP obtaining CDP-DAG
The combination of the non-polar molecule activated will react forming the phosphoglyceride
CTP is the activator of the synthesis of phosphoglycerides
