Patient treated with Purinethol could suffer toxic side effects, why?
They could not remove Purinethol from the body
Purinethol was toxic for them
TPMT inactivated Purinethol
What was the relation between Purinethol and TPMT enzyme?
TPMT removes Purinethol from the body
creates natural Purinethol
TPMT regulates the Purinethol physiological levels
Among the children, how many of them can suffer a fatal side effect and why?
0.33% because they have no TPMT
0.33% because they have no TPMT activity
0.33% because they have high concentration of TPMT
How can we determine the dosage of Purinethol patient need?
A diagnostic test based on genetic information
A diagnostic test based on TPMT concentration
A diagnostic test based on Purinethol resistance
Pharmacogenetic tests allow doctor to:
Determine the most suitable medicine for each patient
Prevent for diseases
Cure infectious diseases
Pharmacogenetic permit people:
Personalize their drug therapies
Prevent side effects
More accurate diagnoses