Bone disease: causes of wear

What is the most common form of arthritis?

What type of wear is caused by two of the same thing rubbing against one another?

What type of wear is a result of two different things rubbing against each other?

What type of wear is involved in osteoarthritis?

What type of wear is involved in rheumatoid arthritis, in which bone rubs against inflamed cartilage?

What is an osteophyte?

What predisposes to attrition between two bones?

List some risk factors for osteoarthritis.

What is rheumatoid arthritis?

Name an inflammatory mediator which can increase osteoclastic activity.

What type of disease is rheumatoid arthritis?

What are matrix metalloproteinases and how are they involved in the development of rheumatoid arthritis?

What is pannus formation with regard to rheumatoid arthritis?

Other than pannus formation, what are some other complications of/features of rheumatoid arthritis?

Given that it is an inflammatory disease with no cure, what type of condition is rheumatoid arthritis?

What three types of mediators are involved in the pathogenesis of rheumatoid arthritis?

Name two pro-inflammatory cytokines that are central mediators in the pathogenesis of rheumatoid arthritis.

In osteoarthritis, mechanical stress is placed on joints. Give three possible reasons for this.

In osteoarthritis there is an overexpression of matrix degrading proteins, including:

What is endochondral ossification?

What is subchondral bone?

When does cartilaginous injury become a problem for subchondral bone?

What is a chondral defect?

What is an osteochondral defect?

What is osteochondritis dessicans?

What is osteomyelitis?

How might osteomyelitis be caused?

What is a common name for osteogenesis imperfecta?

What type of disease is osteogenesis imperfecta?

What is characteristic about osteogenesis imperfecta?

There are four major types of osteogenesis imperfecta. What are these?

What is fibrous dysplasia?

What are three characteristics of fibrous dysplasia?