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Mapa Mental
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Lindie Metz
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? Pathology Mapa Mental sobre 5 CAUSES OF OEDEMA, criado por Lindie Metz em 02-03-2016.
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Lindie Metz
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4718930
mind_map
2016-09-24T00:31:27Z
5 CAUSES OF OEDEMA
Na+ and H2O retention
Decreases plasma colloid P
Lymph obstruction
Increased hydrostatic P
Increased vascular permeability
↓ Venous return
Local
Clot
Systemic
CCF
Constrictive pericarditis
Dilation of arteries
Renal failure
Renal hypoperfusion
Hypoprotonaemia, ↓
albumin in plasma
↓ Absorption
↓ Intake
↓ Synthesis
↑ Loss
GIT – protein losing gastroenteropthy
Kidney – nephrotic syndrome leading
to increased loss in urine
Impairs interstitial
fluid clearance
Inflammation
Cancer
Parasite
Infiltration and obstruction of lymphatics by growth
Treatment causing scarring/loss of lymph drainage
Mass
Inflammation
Systemic
Local
Acute
Chronic
**See CCF diagram, leading to activation of RAAS
DVT causing oedema in distal part of lymb
Causing obstruction, leading to oedema
Ascites
**See note on Liver Cirrhosis leading to ascites
Blood backs up behind the heart and ↑ P
Heat
** See note on Liver Cirrhosis with ascites
Malnutrition
Malabsorption syndrome in GIT
infection by Filariarsis causes obstruction of
inguinal lymphatics (Elephantitis)
Excessive salt intake
↑ Tubular absorption
↑ RAAS
↑ Salt retention
↑ water > ↑ hydrostatic P + ↓ colloid osmotic P
**CCF
**Liver
Cirrhosis
↓ Pump action of heart > ↓ cardiac output > ↓ Renal perfusion > activates RAAS
↑ Na+ and H2O to ↑ blood volume > ↑ hydrostatic P
BUT heart cannot compensate and CO is still ↓ > ↑ Venous back P > ↑ oedema
↓ Liver function > Hypoprotonaemia > ↓ Colloid osmotic P
H2O leaks from vessels > ↓ BV > ↓ Renal perfusion > activates RAAS
↑ Na+ and H2O to ↑ blood volume > ↑ hydrostatic P BUT ↓ Colloid osmotic P
Will get progressively worse > kidney failure
RAAS
Reduced renal perfusion d/t ↓ BF, ↓ BP, dehydration, renal aa stenosis
Kidney releases Renin > Liver > Angiotensinogen > Angiotensin I
Angiotensin II
Vasoconstriction > ↑ BP
Adrenals > Aldosterone> Na+ retention + H2O
ADH > ↑ H2O reabsorption
↑ Thirst, liquid intake, BV
Exudate
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4718930
mind_map
2016-09-24T00:31:27Z
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