Liz Maas
Quiz por , criado more than 1 year ago

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Liz Maas
Criado por Liz Maas mais de 8 anos atrás
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Development of the CNS and Related Birth Defects (CF9)

Development of the CNS and Related Birth Defects (CF9)

Questão 1 de 12

1

The three vesicle stage occurs at the 3rd week of gestation. The five vesicle stage occurs at the 5th week of gestation

Selecione uma das seguintes:

  • both true

  • first true second false

  • first false second true

  • both false

Explicação

Questão 2 de 12

1

The Prechodal plate produces FGF to regulate midline structure development of the brain and face. The Anterior Neural Ridge produces SHH to regulate development of the telencephalon.

Selecione uma das seguintes:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both statements false

Explicação

Questão 3 de 12

1

The prechodal plate is derived from?

Selecione uma das seguintes:

  • Ectoderm

  • Mesoderm

  • Endoderm

  • Dermis

Explicação

Questão 4 de 12

1

The isthmus is between the forebrain and midbrain and regulates their development. It produces both FGF and WNT.

Selecione uma das seguintes:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both false

Explicação

Questão 5 de 12

1

Some neurons from the corpus striatum gives rise to part of the cerebral cortex. Most of the cerebral cortex comes from the pallium.

Selecione uma das seguintes:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both false

Explicação

Questão 6 de 12

1

Which of the following is a vertebral fusion defect where both the neural tissue and meninges protrude?

Selecione uma das seguintes:

  • spina bifida occulta

  • meningocele

  • meningomyelocele

  • myeloschisis

  • Arnold-Chiari malformation

Explicação

Questão 7 de 12

1

Which of the following is incorrectly matched?

Selecione uma das seguintes:

  • Spina Bifida occulta: the bony defect is covered by skin, intact spinal cord

  • Spina Bifida Cystica: there is a protrusion of meninges and neural tissue (meningomyelocele)

  • Meningocele: only the meninges protrude

  • Anencephaly- open brain

  • Craniorachischisis: neural tube defect at the brain and spinal cord

Explicação

Questão 8 de 12

1

In normal development, the spinal cord elongates faster than the vertebral column. In Spina Bifida Cystica, as the vertebral column elongates, the force stretches the spinal cord which causes the herniation of the cerebellum.

Selecione uma das seguintes:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both false

Explicação

Questão 9 de 12

1

The bone most frequently affected by neural tube defects is the occipital bone. Small defects can cause meningoencephalocele.

Selecione uma das seguintes:

  • Both true

  • First true, second false

  • First false, second true

  • Both false

Explicação

Questão 10 de 12

1

Meningoencephalocele is protrusion of just the brain tissue and meninges. Meningohydroencephalocele involves protrusion of the meninges, brain tissue and ventricle.

Selecione uma das seguintes:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both statements false

Explicação

Questão 11 de 12

1

Which of the following is correct?

Selecione uma das seguintes:

  • Lobar HPE- one telencephalic vesicle, one eye, one nasal chamber, other midline defects

  • Alobar HPE- one telencephalic vesicle, one eye, one nasal chamber, other midline defects

  • Smith-Lemli-Opitz involves EMX 2, is autosomal recessive, assorted defects of face, heart, brain, limbs

  • Schizencephaly- involves DHCR 7, causes large clefts in cerebral hemispheres

  • Microcephaly- caused by smaller cranial vault leading to less brain development

Explicação

Questão 12 de 12

1

Hydrocephaly is often due to a blockage in the lateral and third ventricles. The accumulated fluid leads to thinner bones of skull and cerebral cortex and an enlarged head.

Selecione uma das seguintes:

  • Both statements true

  • First true, second false

  • First false, second true

  • Both false.

Explicação

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