Anxiety is an state, ranging from stress to feeling of impending doom.
Name two psychological symptoms of anxiety. 1. 2.
Anxiety causes somatic side effects such as enhanced ❌ activty
Anxiety is affected by disturbances of the systems in the CNS
The major neurotransmitters responsible in the region of the brain are , , and disturbances of .
The section of the brain is responsible for anxiety and fear.
Name two main classes of anxiolytics used. 1. 2.
Benzodiazepines work by binding the site of the receptor and facilitate binding. opens Cl- channel and the membrane.
Name four benzodiazepines. 1. c 2. d 3. o 4. l
Barbiturates work by enhancing the effect of on receptors by binding to the -subunit. They also block receptors. The neurotransmitter binds to the AMPA receptor.
Buspirone is a receptor partial . These are receptors on the -synaptic membrane and act as a feedback mechanism. By agonising this receptor it the production of .
SSRIs are first-line for generalised anxiety disorder.
Sertraline is used first-line for anxiety disorders.