Bacteria can lose and acquire genes to/from the environment using mobile elements that can be shared between species
What is a Pan-Genome?
The sum of all core and accessory genes of a species
The sum of all core and accessory genes of an individual
The sum of all core and accessory genes of a strain
What is the main pathological effect of Horizontal Gene Transfer?
Can make non-pathogen strains pathogenic
Excess DNA damages local cells
Release of DNA diverts bacterial energy to virulence
What is described here- Bacteriophages that have been incorporated into the genome
Prophages
Metaphages
Intephages
Integrated DNA can be stabilised by homologous recombination of the new DNA
Which other methods allow the new DNA strands to integrate?
Persistence of the episome (i,e, freely replicating plasmids)
Integrations by the bacteriophage
Illegitimate incorporation (i.e. Ds break repair)